Abstract Background The neuroglobin (Ngb) is well recognized as a potential biomarker for
the hypoxic‐ischemic brain injury. However, connection between Ngb and delayed cerebral …

Objectives Cell-free hemoglobin in the cerebrospinal fluid (CSF-Hb) may be one of the main
drivers of secondary brain injury after aneurysmal subarachnoid hemorrhage (aSAH) …

Objective This study aims to investigate the genetic predisposition of haptoglobin (Hp)
genotype as a predictor for cerebral vasospasm (CV) after acute subarachnoid hemorrhage …

Background: Haptoglobin (Hp) binds to and facilitates clearance of heme. Compared with
HP 1-1 and 1-2 genotypes, HP 2-2 has a weaker binding affinity and has been linked with …

Hemoglobin (HGB), a potent spasmogen, may cause irreversible damage to the brain after
aneurysm rupture. However, there is no clinical evidence to reveal the relationship between …

Vasospasm after subarachnoid hemorrhage (SAH) is attributable to inflammation and
oxidative stress associated with extracellular hemoglobin (Hb). Haptoglobin (Hp) binds free …

Objectives: Increasing body of experimental and clinical data indicates that early brain injury
after initial bleeding largely contributes to unfavorable outcome after subarachnoid …

Intracerebral hemorrhage (ICH) is a subtype of stoke that may cause significant morbidity
and mortality. Brain injury due to ICH initially occurs within the first few hours as a result of …

Background Cerebral vasospasm is a major contributor to disability and mortality after
aneurysmal subarachnoid hemorrhage. Oxidation of cell-free hemoglobin plays an integral …

Aneurysmal subarachnoid hemorrhage (aSAH) patients develop delayed cerebral ischemia
and delayed deficits (DCI) within 2 weeks of aneurysm rupture at a rate of approximately …