Lung proteomic biomarkers associated with chronic obstructive pulmonary disease

YH Zhang, MR Hoopmann… - … of Physiology-Lung …, 2021 - journals.physiology.org
Identifying protein biomarkers for chronic obstructive pulmonary disease (COPD) has been
challenging. Most previous studies have used individual proteins or preselected protein …

Proteomics-based biomarkers in chronic obstructive pulmonary disease

H Chen, D Wang, C Bai, X Wang - Journal of proteome research, 2010 - ACS Publications
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory lung disease
associated with progressive obstruction of airflow affecting peripheral airways. The …

Analysis of the plasma proteome in COPD: Novel low abundance proteins reflect the severity of lung remodeling

S Merali, CA Barrero, RP Bowler, DE Chen… - COPD: Journal of …, 2014 - Taylor & Francis
The search for COPD biomarkers has largely employed a targeted approach that focuses on
plasma proteins involved in the systemic inflammatory response and in lung injury and …

Blood and sputum protein biomarkers for chronic obstructive pulmonary disease (COPD)

JY Moon, FS Leitao Filho, K Shahangian… - Expert review of …, 2018 - Taylor & Francis
Introduction: Chronic obstructive pulmonary disease (COPD) is a heterogeneous set of
disorders, characterized by airflow limitation, and reduced lung function. Despite increasing …

Differential expression of serum proteins in chronic obstructive pulmonary disease assessed using label-free proteomics and bioinformatics analyses

R Li, X Zhao, P Liu, D Wang, C Chen… - … Journal of Chronic …, 2022 - Taylor & Francis
Purpose As a common respiratory disease, chronic obstructive pulmonary disease (COPD)
has a high morbidity and mortality. Current clinical therapies are not ideal and do not …

Plasma proteomic signatures in early chronic obstructive pulmonary disease

A Baralla, AG Fois, E Sotgiu, E Zinellu… - PROTEOMICS …, 2018 - Wiley Online Library
Purpose Chronic obstructive pulmonary disease (COPD) is characterized by progressive
airflow limitation and abnormal inflammatory response of the lungs to inhaled noxious …

Identification of proteomic signatures associated with lung cancer and COPD

MD Pastor, A Nogal, S Molina-Pinelo, R Melendez… - Journal of …, 2013 - Elsevier
Lung cancer (LC) and chronic obstructive pulmonary disease (COPD) commonly coexist in
smokers, and the presence of COPD increases the risk of developing LC. The aim of this …

Advances in proteomic techniques for biomarker discovery in COPD

B Casado, M Luisetti, P Iadarola - Expert Review of Clinical …, 2011 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is a disorder characterized by chronic
inflammation of the lung with airflow obstruction and progressive deterioration of pulmonary …

Proteomics-based diagnosis of chronic obstructive pulmonary disease: the hunt for new markers

B Casado, P Iadarola, M Luisetti… - Expert review of …, 2008 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is an inflammatory disease characterized by
the progressive deterioration of pulmonary function and irreversible airway obstruction …

Plasma proteomics enable differentiation of lung adenocarcinoma from chronic obstructive pulmonary disease (COPD)

T Bracht, D Kleefisch, K Schork, KE Witzke… - International Journal of …, 2022 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is a major risk factor for the development of
lung adenocarcinoma (AC). AC often develops on underlying COPD; thus, the differentiation …