T cell responses to SARS-CoV-2 spike cross-recognize Omicron

R Keeton, MB Tincho, A Ngomti, R Baguma, N Benede… - Nature, 2022 - nature.com
Abstract The SARS-CoV-2 Omicron variant (B. 1.1. 529) has multiple spike protein
mutations, that contribute to viral escape from antibody neutralization,,–and reduce vaccine …

SARS-CoV-2 spike T cell responses induced upon vaccination or infection remain robust against Omicron

R Keeton, MB Tincho, A Ngomti, R Baguma, N Benede… - MedRxiv, 2021 - medrxiv.org
Summary The SARS-CoV-2 Omicron variant has multiple Spike (S) protein mutations that
contribute to escape from the neutralizing antibody responses, and reducing vaccine …

[HTML][HTML] T cell reactivity to the SARS-CoV-2 Omicron variant is preserved in most but not all individuals

V Naranbhai, A Nathan, C Kaseke, C Berrios, A Khatri… - Cell, 2022 - cell.com
Summary The SARS-CoV-2 Omicron variant (B. 1.1. 529) contains mutations that mediate
escape from antibody responses, although the extent to which these substitutions in spike …

Vaccines elicit highly conserved cellular immunity to SARS-CoV-2 Omicron

J Liu, A Chandrashekar, D Sellers, J Barrett… - Nature, 2022 - nature.com
The highly mutated SARS-CoV-2 Omicron (B. 1.1. 529) variant has been shown to evade a
substantial fraction of neutralizing antibody responses elicited by current vaccines that …

Striking antibody evasion manifested by the Omicron variant of SARS-CoV-2

L Liu, S Iketani, Y Guo, JFW Chan, M Wang, L Liu… - Nature, 2022 - nature.com
Abstract The B. 1.1. 529/Omicron variant of SARS-CoV-2 was only recently detected in
southern Africa, but its subsequent spread has been extensive, both regionally and globally …

Considerable escape of SARS-CoV-2 Omicron to antibody neutralization

D Planas, N Saunders, P Maes, F Guivel-Benhassine… - Nature, 2022 - nature.com
Abstract The SARS-CoV-2 Omicron variant was first identified in November 2021 in
Botswana and South Africa,–. It has since spread to many countries and is expected to …

Spike and nsp6 are key determinants of SARS-CoV-2 Omicron BA. 1 attenuation

DY Chen, CV Chin, D Kenney, AH Tavares, N Khan… - Nature, 2023 - nature.com
Abstract The SARS-CoV-2 Omicron variant is more immune evasive and less virulent than
other major viral variants that have so far been recognized,,,,,,,,,,–. The Omicron spike (S) …

SARS-CoV-2 T cell responses elicited by COVID-19 vaccines or infection are expected to remain robust against Omicron

SF Ahmed, AA Quadeer, MR McKay - Viruses, 2022 - mdpi.com
Omicron, the most recent SARS-CoV-2 variant of concern (VOC), harbours multiple
mutations in the spike protein that were not observed in previous VOCs. Initial studies …

[HTML][HTML] SARS-CoV-2 Omicron neutralization by therapeutic antibodies, convalescent sera, and post-mRNA vaccine booster

S Lusvarghi, SD Pollett, SN Neerukonda, W Wang… - BioRxiv, 2021 - ncbi.nlm.nih.gov
The rapid spread of the highly contagious Omicron variant of SARS-CoV-2 along with its
high number of mutations in the spike gene has raised alarm about the effectiveness of …

Immune responses in Omicron SARS-CoV-2 breakthrough infection in vaccinated adults

H Kared, AS Wolf, A Alirezaylavasani… - Nature …, 2022 - nature.com
Abstract The SARS-CoV-2 Omicron variant has more than 15 mutations in the receptor
binding domain of the Spike protein enabling increased transmissibility and viral escape …