Profile of enfortumab vedotin in the treatment of urothelial carcinoma: the evidence to date

M Moussa, A Papatsoris, M Abou Chakra… - Drug design …, 2021 - Taylor & Francis
Nowadays the therapeutic landscape for advanced and metastatic urothelial carcinoma
continues to evolve. The recent regulatory approval of enfortumab vedotin (EV) for the …

Enfortumab vedotin–next game-changer in urothelial cancer

M Maas, V Stühler, S Walz, A Stenzl… - Expert Opinion on …, 2021 - Taylor & Francis
Introduction: The therapeutic landscape of metastatic urothelial carcinoma (mUC) becomes
increasingly dense: standard therapy remains cisplatin-based chemotherapy, followed by …

Current and Emerging Treatments for Urothelial Carcinoma: A Focus on Enfortumab Vedotin

MA Shafique, A Haseeb, MA Siddiq… - Cancer management …, 2023 - Taylor & Francis
Urothelial carcinoma is a common malignancy that affects the urinary system, with bladder
cancer being the most prevalent form. Although the management of early-stage disease has …

[HTML][HTML] Targeted treatment of locally advanced and metastatic urothelial cancer: enfortumab vedotin in context

J Hoffman-Censits, L Maldonado - OncoTargets and Therapy, 2022 - ncbi.nlm.nih.gov
Enfortumab vedotin (EV) is a novel antibody–drug conjugate that is the first in class to be
FDA-approved for use in patients with treatment-refractory urothelial cancer. Enfortumab is …

Efficacy of enfortumab vedotin in advanced urothelial cancer: analysis from the Urothelial Cancer Network to Investigate Therapeutic Experiences (UNITE) study

VS Koshkin, N Henderson, M James, D Natesan… - Cancer, 2022 - Wiley Online Library
Background Enfortumab vedotin (EV) is a novel antibody‐drug conjugate approved for
advanced urothelial cancer (aUC) refractory to prior therapy. In the Urothelial Cancer …

Clinical overview of enfortumab vedotin in the management of locally advanced or metastatic urothelial carcinoma

KS Hanna - Drugs, 2020 - Springer
The treatment landscape for locally advanced or metastatic urothelial carcinoma has
broadened significantly over recent years. New therapeutic options include immunotherapy …

Efficacy and tolerability of enfortumab vedotin for metastatic urothelial carcinoma: Early experience in the real world

A Minato, R Kimuro, D Ohno, K Tanigawa… - Anticancer …, 2023 - ar.iiarjournals.org
Background/Aim: This study retrospectively investigated the impact of enfortumab vedotin
(EV) monotherapy on the oncological outcome, safety profile, and health-related quality of …

[HTML][HTML] Enfortumab vedotin in metastatic urothelial carcinoma: survival and safety in a European multicenter real-world patient cohort

S Zschäbitz, N Biernath, T Hilser, A Höllein… - European Urology Open …, 2023 - Elsevier
Background Treatment options for patients with urothelial cancer (UC) refractory to platinum
and immunotherapy are limited and survival is short. Enfortumab vedotin (EV) is a …

Enfortumab vedotin in the treatment of urothelial cancers and beyond

RL Wong, EY Yu - Future Oncology, 2022 - Future Medicine
Enfortumab vedotin (EV) is the first antibody–drug conjugate approved for locally advanced
or metastatic urothelial cancers (la/mUCs), a disease group historically associated with …

A phase I study of enfortumab vedotin in Japanese patients with locally advanced or metastatic urothelial carcinoma

S Takahashi, M Uemura, T Kimura, Y Kawasaki… - Investigational new …, 2020 - Springer
Locally advanced or metastatic urothelial cancer is an aggressive form of cancer with high
recurrence rates and low survival. Nectin-4 is a cell adhesion molecule commonly …