Neutrophils are frontline cells of the innate immune system. These effector leukocytes are
equipped with intriguing antimicrobial machinery and consequently display high cytotoxic …

Neutrophils are the primary cells recruited to inflamed sites during an innate immune
response to tissue damage and/or infection. They are finely sensitive to inciting stimuli to …

Neutrophils play a critical role in the host defense against bacterial and fungal infections, but
their inappropriate activation also contributes to tissue damage during autoimmune and …

Neutrophils are pivotal effector cells of innate immunity. Their recruitment into peripheral
tissues is indispensable for host defense. Given their destructive potential, neutrophil entry …

Chemokines play crucial roles in combating microbial infection and initiating tissue repair by
recruiting neutrophils in a timely and coordinated manner. In humans, no less than seven …

Chemokines are recognized as the most critical mediators for selective neutrophil
recruitment during inflammatory conditions. Furthermore, they are considered fundamental …

Neutrophil granulocytes, or neutrophils, are the most abundant circulating leukocytes in
humans and indispensable for antimicrobial immunity, as exemplified in patients with inborn …

For the past twenty years, chemokines have emerged as a family of critical mediators of cell
migration during immune surveillance, development, inflammation and cancer progression …

Polymorphonuclear neutrophils (PMNs) are the most abundant leukocytes in the blood and
constitute the first line of host defense against numerous infectious pathogens, including …

Neutrophils are classically considered as cells pivotal for the first line of defense against
invading pathogens. In recent years, evidence has accumulated that they are also important …