Neutralization of SARS-CoV-2 Omicron by BNT162b2 mRNA vaccine–elicited human sera

A Muik, BG Lui, AK Wallisch, M Bacher, J Mühl… - Science, 2022 - science.org
The globally circulating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variant of concern Omicron (B. 1.1. 529) has a large number of mutations, especially in the …

[HTML][HTML] The SARS-CoV-2 spike S375F mutation characterizes the Omicron BA. 1 variant

I Kimura, D Yamasoba, H Nasser, J Zahradnik… - Iscience, 2022 - cell.com
Recent studies have revealed the unique virological characteristics of Omicron, particularly
those of its spike protein, such as less cleavage efficacy in cells, reduced ACE2 binding …

A correlate of protection for SARS-CoV-2 vaccines is urgently needed

F Krammer - Nature medicine, 2021 - nature.com
A correlate of protection for SARS-CoV-2 vaccines is urgently needed | Nature Medicine Skip to
main content Thank you for visiting nature.com. You are using a browser version with limited …

Omicron entry route

L Pia, S Rowland-Jones - Nature Reviews Immunology, 2022 - nature.com
Magnesium: essential for T cells Page 1 www.nature.com/nri 0123456789();: Tumour necrosis
factor (TNF)induced cell death is both a driver and consequence of chronic inflammation in …

Improved neutralisation of the SARS-CoV-2 Omicron variant following a booster dose of Pfizer-BioNTech (BNT162b2) COVID-19 vaccine

K Basile, RJ Rockett, K McPhie, M Fennell… - Viruses, 2022 - mdpi.com
In late November 2021, the World Health Organization declared the SARS-CoV-2 lineage B.
1.1. 529 the fifth variant of concern, Omicron. This variant has acquired over 30 mutations in …

SARS-CoV-2 BA. 1 variant is neutralized by vaccine booster–elicited serum but evades most convalescent serum and therapeutic antibodies

S Lusvarghi, SD Pollett, SN Neerukonda… - Science Translational …, 2022 - science.org
The rapid spread of the highly contagious Omicron variant of severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) along with its high number of mutations in the spike …

[HTML][HTML] Antibody titers and breakthrough infections with Omicron SARS-CoV-2

C Dimeglio, M Migueres, JM Mansuy… - The Journal of …, 2022 - ncbi.nlm.nih.gov
Recent studies indicated that the strong immune evasion potential of the most recent SARS-
CoV-2 variant, Omicron, results in more frequent reinfections and breakthrough infections …

Reduced neutralization of SARS-CoV-2 Omicron variant by vaccine sera and monoclonal antibodies

A Wilhelm, M Widera, K Grikscheit, T Toptan, B Schenk… - MedRxiv, 2021 - medrxiv.org
Due to numerous mutations in the spike protein, the SARS-CoV-2 variant of concern
Omicron (B. 1.1. 529) raises serious concerns since it may significantly limit the antibody …

SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway

BJ Willett, J Grove, OA MacLean, C Wilkie… - Nature …, 2022 - nature.com
Vaccines based on the spike protein of SARS-CoV-2 are a cornerstone of the public health
response to COVID-19. The emergence of hypermutated, increasingly transmissible variants …

Therapeutic efficacy of monoclonal antibodies and antivirals against SARS-CoV-2 Omicron BA. 1 in Syrian hamsters

R Uraki, M Kiso, M Imai, S Yamayoshi, M Ito… - Nature …, 2022 - nature.com
The spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the
major antigen stimulating the host's protective immune response. Here we assessed the …