Multiple studies implicate iron accumulation in the substantia nigra in the degeneration of
dopaminergic neurons in Parkinson's disease. Indeed, slowing of iron accumulation in cells …

Neuronal iron homeostasis disruption and oxidative stress are closely related to the
pathogenesis of Parkinson's disease (PD). Adult iron-regulatory protein 2 knockout (Ireb2 …

The aim of our study was to investigate to investigate the effect of myricetin on Alzheimer's
disease (AD) and its underlying mechanisms. In our study, Myricetin effectively attenuated …

Iron accumulation in the substantia nigra is recognized as a hallmark of Parkinson's disease
(PD). Therefore, reducing accumulated iron and associated oxidative stress is considered a …

Hepcidin, a master regulator of iron homeostasis, is a promising target in treatment of iron
disorders such as hemochromatosis, anemia of inflammation and iron-deficiency anemia …

Ferritin is the main iron storage protein and plays an important role in maintaining iron
homeostasis. In a previous study, we reported that apoferritin exerted a neuroprotective …

Abstract Aims: Mitochondrial ferritin (MtFt), which was recently discovered, plays an
important role in preventing neuronal damage in 6-hydroxydopamine-induced Parkinsonism …

Despite intensive research on Parkinson disease (PD) for decades, this common
neurodegenerative disease remains incurable. We hypothesize that abnormal iron …

Ferroptosis, a newly identified iron-dependent form of cell death, has recently been
implicated in the pathogenesis of Parkinson's disease (PD). Dl-3-n-butylphthalide (NBP) …

Previous studies have shown that baicalin prevented iron accumulation after substantia
nigra injury, reduced divalent metal transporter 1 expression, and increased ferroportin 1 …