Comparison of oleocanthal-low EVOO and oleocanthal against amyloid-β and related pathology in a mouse model of alzheimer's disease

IM Abdallah, KM Al-Shami, AE Alkhalifa… - Molecules, 2023 - mdpi.com
Alzheimer's disease (AD) is characterized by several pathological hallmarks, including the
deposition of amyloid-β (Aβ) plaques, neurofibrillary tangles, blood–brain barrier (BBB) …

Anti-Cancer, Anti-Angiogenic, and Anti-Atherogenic Potential of Key Phenolic Compounds from Virgin Olive Oil

AD Marrero, AR Quesada, B Martínez-Poveda… - Nutrients, 2024 - mdpi.com
The Mediterranean diet, renowned for its health benefits, especially in reducing
cardiovascular risks and protecting against diseases like diabetes and cancer, emphasizes …

Modulation of tau protein fibrillization by oleocanthal

MC Monti, L Margarucci, R Riccio… - Journal of natural …, 2012 - ACS Publications
Among the phenolic compounds extracted from extra virgin olive oil, oleocanthal (1) has
attracted considerable attention in the modulation of many human diseases, such as …

Potential therapeutic effects of oleuropein aglycone in Alzheimer's disease

M Martorell, K Forman, N Castro, X Capo… - Current …, 2016 - ingentaconnect.com
Alzheimer's disease (AD) is an age-associated neurodegenerative amyloid disease and is
considered a social and clinical problem the last decades, particularly in the Western …

Oleuropein aglycone: a possible drug against degenerative conditions. In vivo evidence of its effectiveness against Alzheimer's disease

F Casamenti, C Grossi, S Rigacci… - Journal of …, 2015 - content.iospress.com
The amyloid plaques and neurofibrillary tangles found in the Alzheimer's disease (AD) brain
arise as a result of self-assembly into fibrillar material of amyloid-β protein (Aβ) and …

Natural molecules for healthy lifestyles: Oleocanthal from extra virgin olive oil

V Francisco, C Ruiz-Fernández, V Lahera… - Journal of agricultural …, 2019 - ACS Publications
Extra virgin olive oil (EVOO) is the main source of fat in the Mediterranean diet. Phenolic
compounds of EVOO, in particular, secoiridoids, are minor components that have generated …

Storage of extra virgin olive oil and its effect on the biological activity and concentration of oleocanthal

S Cicerale, XA Conlan, NW Barnett… - Food research international, 2013 - Elsevier
The olive oil phenolic, oleocanthal has recently received attention regarding its anti-
inflammatory capacity and the thought that it is partially responsible for the beneficial health …

Anticancer potential of oleuropein, the polyphenol of olive oil, with 2-methoxyestradiol, separately or in combination, in human osteosarcoma cells

P Przychodzen, R Wyszkowska… - Anticancer …, 2019 - ar.iiarjournals.org
Background/Aim: Oleuropein belongs to the potent polyphenols of olive oil. Notably, it is
considered as a potentially active anticancer agent. Herein, the anticancer efficiency of …

A comprehensive review on the anti-cancer effects of oleuropein

S Rishmawi, F Haddad, G Dokmak, R Karaman - Life, 2022 - mdpi.com
In Mediterranean cuisine and culture, olive oil and olive fruits play a significant role. Many
people believe that those who consume olive oil and its fruit live longer and have a …

Benefits of olive oil phenolic compounds in disease prevention

O Garcia-Martinez, C Ruiz… - … Metabolic & Immune …, 2018 - ingentaconnect.com
Background and Objective: The preventive effects of olive oil against different diseases have
been attributed to its high phenolic compound content. The objective of this study was to …