Assessment of the anti-inflammatory, analgesic and sedative effects of oleuropein from Olea europaea L

X Mao, B Xia, M Zheng, Z Zhou - Cellular and Molecular …, 2019 - mail.cellmolbiol.org
More and more studies show that inflammation, pain and insomnia have become the main
common diseases. Effective treatments of inflammation, pain and insomnia have become an …

Analgesic, anti‐inflammatory and anticancer activities of extra virgin olive oil

M Fezai, L Senovilla, M Jemaà, M Ben-Attia - Journal of lipids, 2013 - Wiley Online Library
Background. In folk medicine, extra virgin olive oil (EVOO) is used as a remedy for a variety
of diseases. This study investigates the in vivo antinociceptive, anti‐inflammatory, and anti …

Chemopreventive properties of pinoresinol-rich olive oil involve a selective activation of the ATM–p53 cascade in colon cancer cell lines

L Fini, E Hotchkiss, V Fogliano, G Graziani… - …, 2008 - academic.oup.com
The Mediterranean diet is rich in extra virgin olive oil (EVOO) and associated with a lower
incidence of colorectal cancer. EVOO contains phenolic extracts with potential …

Structure–biological activity relationships of extra-virgin olive oil phenolic compounds: Health properties and bioavailability

P Rodríguez-López, J Lozano-Sanchez… - Antioxidants, 2020 - mdpi.com
Extra-virgin olive oil is regarded as functional food since epidemiological studies and
multidisciplinary research have reported convincing evidence that its intake affects …

Epigenetic modifications induced by olive oil and its phenolic compounds: A systematic review

R Fabiani, N Vella, P Rosignoli - Molecules, 2021 - mdpi.com
Many studies demonstrated that olive oil (especially extra virgin olive oil: EVOO) phenolic
compounds are bioactive molecules with anti-cancer, anti-inflammatory, anti-aging and …

Evidence to support the anti-cancer effect of olive leaf extract and future directions

A Boss, KS Bishop, G Marlow, MPG Barnett… - Nutrients, 2016 - mdpi.com
The traditional Mediterranean diet (MD) is associated with long life and lower prevalence of
cardiovascular disease and cancers. The main components of this diet include high intake of …

Oleacein attenuates lipopolysaccharide-induced inflammation in THP-1-derived macrophages by the inhibition of TLR4/MyD88/NF-κB pathway

S Cirmi, A Maugeri, C Russo, L Musumeci… - International Journal of …, 2022 - mdpi.com
It is known that plant phenolic compounds exert anti-inflammatory activity through both anti-
oxidant effects and modulation of pivotal pro-inflammatory factors. Recently, Olea europaea …

Protective role of oleuropein and its metabolite hydroxytyrosol on cancer

MP Carrera-González, MJ Ramírez-Expósito… - Trends in food science & …, 2013 - Elsevier
Most therapies do not discriminate between normal and cancerous cells, leading to toxicity
and unwanted side effects. In this sense, the oleuropein, minor component of extra virgin …

Anti-proliferative and apoptotic effects of oleuropein and hydroxytyrosol on human breast cancer MCF-7 cells

J Han, TPN Talorete, P Yamada, H Isoda - Cytotechnology, 2009 - Springer
Olive oil intake has been shown to induce significant levels of apoptosis in various cancer
cells. These anti-cancer properties are thought to be mediated by phenolic compounds …

Olive oil compounds inhibit the paracrine regulation of TNF-α-induced endothelial cell migration through reduced glioblastoma cell cyclooxygenase-2 expression

S Lamy, AB Saad, A Zgheib, B Annabi - The Journal of Nutritional …, 2016 - Elsevier
The established causal relationship between the chronic inflammatory microenvironment,
tumor development and cancer recurrence has provided leads for developing novel …