[HTML][HTML] Cross-talk signaling in the trigeminal ganglion: role of neuropeptides and other mediators

K Messlinger, LK Balcziak, AF Russo - Journal of neural transmission, 2020 - Springer
The trigeminal ganglion with its three trigeminal nerve tracts consists mainly of clusters of
sensory neurons with their peripheral and central processes. Most neurons are surrounded …

Neuron–glia signaling in trigeminal ganglion: implications for migraine pathology

S Thalakoti, VV Patil, S Damodaram… - … : The Journal of …, 2007 - Wiley Online Library
Objective.—The goal of this study was to investigate neuronal–glial cell signaling in
trigeminal ganglia under basal and inflammatory conditions using an in vivo model of …

Current understanding of trigeminal ganglion structure and function in headache

K Messlinger, AF Russo - Cephalalgia, 2019 - journals.sagepub.com
Introduction The trigeminal ganglion is unique among the somatosensory ganglia regarding
its topography, structure, composition and possibly some functional properties of its cellular …

[HTML][HTML] Recent advances in basic research on the trigeminal ganglion

T Goto, SB Oh, M Takeda, M Shinoda, T Sato… - The journal of …, 2016 - Springer
Peripheral tissue inflammation can alter the properties of somatic sensory pathways,
causing behavioral hypersensitivity and resulting in increased responses to pain caused by …

CGRP and the trigeminal system in migraine

S Iyengar, KW Johnson, MH Ossipov… - … : The Journal of Head …, 2019 - Wiley Online Library
Objective The goal of this narrative review is to provide an overview of migraine
pathophysiology, with an emphasis on the role of calcitonin gene‐related peptide (CGRP) …

Calcitonin gene-related peptide-mediated enhancement of purinergic neuron/glia communication by the algogenic factor bradykinin in mouse trigeminal ganglia from …

S Ceruti, G Villa, M Fumagalli, L Colombo… - Journal of …, 2011 - Soc Neuroscience
Within the trigeminal ganglion, crosstalk between neurons and satellite glial cells (SGCs)
contributes to neuronal sensitization and transduction of painful stimuli, including migraine …

Unitary hypothesis for multiple triggers of the pain and strain of migraine

R Burstein, M Jakubowski - Journal of comparative neurology, 2005 - Wiley Online Library
Migraine headache is triggered by and associated with a variety of hormonal, emotional,
nutritional, and physiological changes. The perception of migraine headache is formed …

Meningeal afferent signaling and the pathophysiology of migraine

C Burgos-Vega, J Moy, G Dussor - Progress in molecular biology and …, 2015 - Elsevier
Migraine is the most common neurological disorder. Attacks are complex and consist of
multiple phases but are most commonly characterized by intense, unilateral, throbbing …

General trigeminospinal central sensitization and impaired descending pain inhibitory controls contribute to migraine progression

N Boyer, R Dallel, A Artola, L Monconduit - Pain, 2014 - journals.lww.com
Progressively impaired descending inhibition and potentiated general trigeminospinal
hypersensitivity participate in the worsening, spatial spreading persistence of cutaneous …

[HTML][HTML] TRP channels in the focus of trigeminal nociceptor sensitization contributing to primary headaches

M Dux, J Rosta, K Messlinger - International journal of molecular sciences, 2020 - mdpi.com
Pain in trigeminal areas is driven by nociceptive trigeminal afferents. Transduction
molecules, among them the nonspecific cation channels transient receptor potential …