[HTML][HTML] Exosomes derived from GDNF-modified human adipose mesenchymal stem cells ameliorate peritubular capillary loss in tubulointerstitial fibrosis by activating …
L Chen, Y Wang, S Li, B Zuo, X Zhang, F Wang… - Theranostics, 2020 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) have emerged as ideal cell-based therapeutic candidates
for the structural and functional restoration of the diseased kidney. Glial cell line-derived …
for the structural and functional restoration of the diseased kidney. Glial cell line-derived …
Exosomes from human adipose-derived mesenchymal stromal/stem cells accelerate angiogenesis in wound healing: implication of the EGR-1/lncRNA-SENCR/DKC1 …
Y Sun, Y Ju, B Fang - Human cell, 2022 - Springer
Exosomes (Exos) extracted from human adipose mesenchymal stromal/stem cells (hAD-
MSCs) have been reported as therapeutic tools for tissue repair, but how they regulate …
MSCs) have been reported as therapeutic tools for tissue repair, but how they regulate …
[HTML][HTML] Exosomes derived from mesenchymal stem cells ameliorate renal ischemic-reperfusion injury through inhibiting inflammation and cell apoptosis
This study aimed to investigate the underlying mechanism of mesenchymal stem cells
(MSCs) on protection of renal ischemia reperfusion injury (IRI). Exosomes originated from …
(MSCs) on protection of renal ischemia reperfusion injury (IRI). Exosomes originated from …
[HTML][HTML] Bone marrow mesenchymal stem cell-derived exosomal miR-21a-5p alleviates renal fibrosis by attenuating glycolysis by targeting PFKM
S Xu, YC Cheuk, Y Jia, T Chen, J Chen, Y Luo… - Cell death & …, 2022 - nature.com
Renal fibrosis is a common pathological feature and outcome of almost all chronic kidney
diseases, and it is characterized by metabolic reprogramming toward aerobic glycolysis …
diseases, and it is characterized by metabolic reprogramming toward aerobic glycolysis …
[HTML][HTML] Exosomes from high glucose-treated glomerular endothelial cells trigger the epithelial-mesenchymal transition and dysfunction of podocytes
X Wu, Y Gao, L Xu, W Dang, H Yan, D Zou, Z Zhu… - Scientific reports, 2017 - nature.com
New data indicate that abnormal glomerular endothelial cell (GEC)-podocyte crosstalk plays
a critical role in diabetic nephropathy (DN). The aim of our study is to investigate the role of …
a critical role in diabetic nephropathy (DN). The aim of our study is to investigate the role of …
[HTML][HTML] Mesenchymal stem cell-derived extracellular vesicles to the rescue of renal injury
L Birtwistle, XM Chen, C Pollock - International Journal of Molecular …, 2021 - mdpi.com
Acute kidney injury (AKI) and chronic kidney disease (CKD) are rising in global prevalence
and cause significant morbidity for patients. Current treatments are limited to slowing instead …
and cause significant morbidity for patients. Current treatments are limited to slowing instead …
[HTML][HTML] Mesenchymal stem cell therapy ameliorates diabetic nephropathy via the paracrine effect of renal trophic factors including exosomes
K Nagaishi, Y Mizue, T Chikenji, M Otani, M Nakano… - Scientific reports, 2016 - nature.com
Bone marrow-derived mesenchymal stem cells (MSCs) have contributed to the improvement
of diabetic nephropathy (DN); however, the actual mediator of this effect and its role has not …
of diabetic nephropathy (DN); however, the actual mediator of this effect and its role has not …
[HTML][HTML] Reproducible large-scale isolation of exosomes from adipose tissue-derived mesenchymal stem/stromal cells and their application in acute kidney injury
Acute kidney injury (AKI) is a fatal medical episode caused by sudden kidney damage or
failure, leading to the death of patients within a few hours or days. Previous studies …
failure, leading to the death of patients within a few hours or days. Previous studies …
[HTML][HTML] Mesenchymal stem cell–derived extracellular vesicles attenuate kidney inflammation
A Eirin, XY Zhu, AS Puranik, H Tang, KA McGurren… - Kidney international, 2017 - Elsevier
Mesenchymal stem/stromal cells (MSCs) have distinct capability for renal repair, but may
have safety concerns. MSC-derived extracellular vesicles emerged as a novel noncellular …
have safety concerns. MSC-derived extracellular vesicles emerged as a novel noncellular …
Mesenchymal stem cells attenuate renal fibrosis via exosomes-mediated delivery of microRNA Let-7i-5p antagomir
J Jin, F Qian, D Zheng, W He, J Gong… - International journal of …, 2021 - Taylor & Francis
Background Renal fibrosis is a chronic and progressive process affecting kidneys in chronic
kidney disease (CKD). Mesenchymal stem cells-derived exosomes (MSCs-Exo) have been …
kidney disease (CKD). Mesenchymal stem cells-derived exosomes (MSCs-Exo) have been …
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