[HTML][HTML] Exosomes derived from GDNF-modified human adipose mesenchymal stem cells ameliorate peritubular capillary loss in tubulointerstitial fibrosis by activating …

L Chen, Y Wang, S Li, B Zuo, X Zhang, F Wang… - Theranostics, 2020 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) have emerged as ideal cell-based therapeutic candidates
for the structural and functional restoration of the diseased kidney. Glial cell line-derived …

Exosomes from human adipose-derived mesenchymal stromal/stem cells accelerate angiogenesis in wound healing: implication of the EGR-1/lncRNA-SENCR/DKC1 …

Y Sun, Y Ju, B Fang - Human cell, 2022 - Springer
Exosomes (Exos) extracted from human adipose mesenchymal stromal/stem cells (hAD-
MSCs) have been reported as therapeutic tools for tissue repair, but how they regulate …

[HTML][HTML] Exosomes derived from mesenchymal stem cells ameliorate renal ischemic-reperfusion injury through inhibiting inflammation and cell apoptosis

L Li, R Wang, Y Jia, R Rong, M Xu, T Zhu - Frontiers in Medicine, 2019 - frontiersin.org
This study aimed to investigate the underlying mechanism of mesenchymal stem cells
(MSCs) on protection of renal ischemia reperfusion injury (IRI). Exosomes originated from …

[HTML][HTML] Bone marrow mesenchymal stem cell-derived exosomal miR-21a-5p alleviates renal fibrosis by attenuating glycolysis by targeting PFKM

S Xu, YC Cheuk, Y Jia, T Chen, J Chen, Y Luo… - Cell death & …, 2022 - nature.com
Renal fibrosis is a common pathological feature and outcome of almost all chronic kidney
diseases, and it is characterized by metabolic reprogramming toward aerobic glycolysis …

[HTML][HTML] Exosomes from high glucose-treated glomerular endothelial cells trigger the epithelial-mesenchymal transition and dysfunction of podocytes

X Wu, Y Gao, L Xu, W Dang, H Yan, D Zou, Z Zhu… - Scientific reports, 2017 - nature.com
New data indicate that abnormal glomerular endothelial cell (GEC)-podocyte crosstalk plays
a critical role in diabetic nephropathy (DN). The aim of our study is to investigate the role of …

[HTML][HTML] Mesenchymal stem cell-derived extracellular vesicles to the rescue of renal injury

L Birtwistle, XM Chen, C Pollock - International Journal of Molecular …, 2021 - mdpi.com
Acute kidney injury (AKI) and chronic kidney disease (CKD) are rising in global prevalence
and cause significant morbidity for patients. Current treatments are limited to slowing instead …

[HTML][HTML] Mesenchymal stem cell therapy ameliorates diabetic nephropathy via the paracrine effect of renal trophic factors including exosomes

K Nagaishi, Y Mizue, T Chikenji, M Otani, M Nakano… - Scientific reports, 2016 - nature.com
Bone marrow-derived mesenchymal stem cells (MSCs) have contributed to the improvement
of diabetic nephropathy (DN); however, the actual mediator of this effect and its role has not …

[HTML][HTML] Reproducible large-scale isolation of exosomes from adipose tissue-derived mesenchymal stem/stromal cells and their application in acute kidney injury

JH Lee, DH Ha, H Go, J Youn, H Kim, RC Jin… - International Journal of …, 2020 - mdpi.com
Acute kidney injury (AKI) is a fatal medical episode caused by sudden kidney damage or
failure, leading to the death of patients within a few hours or days. Previous studies …

[HTML][HTML] Mesenchymal stem cell–derived extracellular vesicles attenuate kidney inflammation

A Eirin, XY Zhu, AS Puranik, H Tang, KA McGurren… - Kidney international, 2017 - Elsevier
Mesenchymal stem/stromal cells (MSCs) have distinct capability for renal repair, but may
have safety concerns. MSC-derived extracellular vesicles emerged as a novel noncellular …

Mesenchymal stem cells attenuate renal fibrosis via exosomes-mediated delivery of microRNA Let-7i-5p antagomir

J Jin, F Qian, D Zheng, W He, J Gong… - International journal of …, 2021 - Taylor & Francis
Background Renal fibrosis is a chronic and progressive process affecting kidneys in chronic
kidney disease (CKD). Mesenchymal stem cells-derived exosomes (MSCs-Exo) have been …