[HTML][HTML] Exosomes from adipose-derived stem cells inhibit inflammation and oxidative stress in LPS-acute kidney injury

W Zhang, J Zhang, H Huang - Experimental cell research, 2022 - Elsevier
Acute renal damage presents a significant danger to kidney health. Previous research has
found that acute kidney injury shows high levels of oxidative stress and inflammation caused …

[HTML][HTML] Extracellular vesicles produced by bone marrow mesenchymal stem cells attenuate renal fibrosis, in part by inhibiting the RhoA/ROCK pathway, in a UUO rat …

Z Shi, Q Wang, Y Zhang, D Jiang - Stem cell research & therapy, 2020 - Springer
Background Extracellular vesicles produced by bone marrow mesenchymal stem cells
(BMSC-EVs) can play important roles in the repair of injured tissues. Though numerous …

[HTML][HTML] Human adipose mesenchymal stem cells modulate inflammation and angiogenesis through exosomes

JS Heo, S Kim - Scientific Reports, 2022 - nature.com
Stem cell-derived exosomes are efficient and safe therapeutic tools for transferring
endogenous biological cargo or functional biomolecules for regenerative medicine. The …

[HTML][HTML] Exosomes from mmu_circ_0001052-modified adipose-derived stem cells promote angiogenesis of DFU via miR-106a-5p and FGF4/p38MAPK pathway

ZH Liang, NF Pan, SS Lin, ZY Qiu, P Liang… - Stem cell research & …, 2022 - Springer
Background Diabetic foot ulcer (DFU) is a chronic infectious disease caused by diabetes
mellitus (DM). Angiogenesis plays the decisive role in wound healing of DFU. Adipose …

[HTML][HTML] Exosome secreted from adipose-derived stem cells attenuates diabetic nephropathy by promoting autophagy flux and inhibiting apoptosis in podocyte

J Jin, Y Shi, J Gong, L Zhao, Y Li, Q He… - Stem cell research & …, 2019 - Springer
Background It is confirmed that adipose-derived stem cells (ADSCs) transplantation
effectively relieves kidney fibrosis and type 2 diabetes disease in mice. Currently, exosome …

[HTML][HTML] Exosomal miR-125b-5p deriving from mesenchymal stem cells promotes tubular repair by suppression of p53 in ischemic acute kidney injury

JY Cao, B Wang, TT Tang, Y Wen, ZL Li, ST Feng… - Theranostics, 2021 - ncbi.nlm.nih.gov
Mesenchymal stem cells-derived exosomes (MSC-exos) have attracted great interest as a
cell-free therapy for acute kidney injury (AKI). However, the in vivo biodistribution of MSC …

Protective function of exosomes from adipose tissue-derived mesenchymal stem cells in acute kidney injury through SIRT1 pathway

F Gao, B Zuo, Y Wang, S Li, J Yang, D Sun - Life sciences, 2020 - Elsevier
Aims To investigate the protective function of exosomes from adipose tissue-derived
mesenchymal stem cells (AMSCs) in sepsis-induced acute kidney injury (AKI) in mice and …

Mesenchymal stem cell–derived extracellular vesicles induce regulatory T cells to ameliorate chronic kidney injury

T Song, A Eirin, X Zhu, Y Zhao, JD Krier, H Tang… - …, 2020 - Am Heart Assoc
Metabolic syndrome (MetS) profoundly changes the contents of mesenchymal stem cells
and mesenchymal stem cells–derived extracellular vesicles (EVs). The anti-inflammatory …

Exosomes from high glucose-treated glomerular endothelial cells activate mesangial cells to promote renal fibrosis

X Wu, Y Gao, F Cui, N Zhang - Biology Open, 2016 - journals.biologists.com
The interaction between glomerular endothelial cells (GECs) and glomerular mesangial
cells (GMCs) is an essential aspect of diabetic nephropathy (DN). Therefore, understanding …

[HTML][HTML] Mesenchymal stem cells-derived exosomes ameliorate ischemia/reperfusion induced acute kidney injury in a porcine model

J Huang, H Cao, B Cui, X Ma, L Gao, C Yu… - Frontiers in cell and …, 2022 - frontiersin.org
Exosomes are membrane-enclosed vesicles secreted by cells, containing a variety of
biologically active ingredients including proteins, nucleic acids and lipids. In this study, we …