Exosomes derived from hucMSC attenuate renal fibrosis through CK1δ/β-TRCP-mediated YAP degradation
C Ji, J Zhang, Y Zhu, H Shi, S Yin, F Sun, Q Wang… - Cell Death & …, 2020 - nature.com
Exosomes from human umbilical cord mesenchymal stem cells (hucMSC-Ex) have been
suggested as novel nanomaterials for regenerative medicine. Here we explored the roles of …
suggested as novel nanomaterials for regenerative medicine. Here we explored the roles of …
Stem cell-derived extracellular vesicles inhibit and revert fibrosis progression in a mouse model of diabetic nephropathy
C Grange, S Tritta, M Tapparo, M Cedrino, C Tetta… - Scientific reports, 2019 - nature.com
Extracellular vesicles (EVs) that are derived from mesenchymal stromal cells (MSCs) have
been shown to reprogram injured cells by activating regenerative processes. We herein …
been shown to reprogram injured cells by activating regenerative processes. We herein …
[HTML][HTML] Human mesenchymal stromal cell-derived extracellular vesicles alleviate renal ischemic reperfusion injury and enhance angiogenesis in rats
X Zou, D Gu, X Xing, Z Cheng, D Gong… - American journal of …, 2016 - ncbi.nlm.nih.gov
Background: Mesenchymal stromal cells (MSCs) derived extracellular vesicles (EVs) were
regarded as a potent medium for kidney injury repair and angiogenesis were regarded as …
regarded as a potent medium for kidney injury repair and angiogenesis were regarded as …
TGF-β1–containing exosomes from injured epithelial cells activate fibroblasts to initiate tissue regenerative responses and fibrosis
Hypoxia is associated with tissue injury and fibrosis but its functional role in fibroblast
activation and tissue repair/regeneration is unknown. Using kidney injury as a model …
activation and tissue repair/regeneration is unknown. Using kidney injury as a model …
Mesenchymal stem cell-derived microparticles ameliorate peritubular capillary rarefaction via inhibition of endothelial-mesenchymal transition and decrease …
HY Choi, HG Lee, BS Kim, SH Ahn, A Jung… - Stem cell research & …, 2015 - Springer
Abstract Introduction Microparticles (MPs) derived from kidney-derived mesenchymal stem
cells (KMSCs) have recently been reported to ameliorate rarefaction of peritubular …
cells (KMSCs) have recently been reported to ameliorate rarefaction of peritubular …
Mesenchymal Stem/Stromal Cell–Derived Extracellular Vesicles for Chronic Kidney Disease: Are We There Yet?
A Eirin, LO Lerman - Hypertension, 2021 - Am Heart Assoc
Mesenchymal stem/stromal cells (MSCs) are the most utilized cell type for cellular therapy,
partly due to their important proliferative potential and ability to differentiate into various cell …
partly due to their important proliferative potential and ability to differentiate into various cell …
In Vivo Tracking of Mesenchymal Stem Cell-Derived Extracellular Vesicles Improving Mitochondrial Function in Renal Ischemia–Reperfusion Injury
H Cao, Y Cheng, H Gao, J Zhuang, W Zhang, Q Bian… - ACS …, 2020 - ACS Publications
Extracellular vesicles (EVs) released by mesenchymal stem cells (MSCs) have exhibited
regenerative capability in animal models of ischemia–reperfusion (I/R) acute kidney injury …
regenerative capability in animal models of ischemia–reperfusion (I/R) acute kidney injury …
Low serum cultured adipose tissue-derived stromal cells ameliorate acute kidney injury in rats
T Katsuno, T Ozaki, Y Saka, K Furuhashi… - Cell …, 2013 - journals.sagepub.com
Current studies suggest that mesenchymal stromal cells (MSCs) improve acute kidney injury
(AKI) via paracrine/endocrine effects. We established human adipose tissue-derived stromal …
(AKI) via paracrine/endocrine effects. We established human adipose tissue-derived stromal …
Exosomes from human‐bone‐marrow‐derived mesenchymal stem cells protect against renal ischemia/reperfusion injury via transferring miR‐199a‐3p
G Zhu, L Pei, F Lin, H Yin, X Li, W He… - Journal of cellular …, 2019 - Wiley Online Library
Renal ischemia/reperfusion (I/R) injury is the main reason for acute kidney injury (AKI) and is
closely related to high morbidity and mortality. In this study, we found that exosomes from …
closely related to high morbidity and mortality. In this study, we found that exosomes from …
Enhanced proangiogenic potential of mesenchymal stem cell-derived exosomes stimulated by a nitric oxide releasing polymer
Mesenchymal stem cell (MSC)-derived exosomes have been recognized as new candidates
for the treatment of degenerative diseases or injury and may provide an alternative to cell …
for the treatment of degenerative diseases or injury and may provide an alternative to cell …