Extracellular vesicles such as exosomes are involved in mediating cell-cell communication
by shuttling an assortment of proteins and genetic information. Here, we tested whether …

Kidney repair following injury involves the reconstitution of a structurally and functionally
intact tubular epithelium. Growth factors and their receptors, such as EGFR, are important in …

Mesenchymal stem cells (MSCs) have immunomodulatory and regenerative effects in many
organs, including the kidney. Emerging evidence has shown that the trophic effects from …

Kidney diseases pose a threat to human health due to their rising incidence and fatality rate.
In preclinical and clinical studies, it has been acknowledged that mesenchymal stem cells …

Mesenchymal stem cells (MSC) are known to facilitate healing of ischemic tissue related
diseases through proangiogenic secretory proteins. Recent studies further show that MSC …

Mesenchymal stem cells (MSCs) have been found to benefit patients with a variety of
ischemic diseases via promoting angiogenesis. It is also well established that exosomes …

Mesenchymal stem cells (MSCs) have beneficial effects on wound healing. MSCs function
through direct cell-cell communication or indirectly through paracrine secretion of exosomes …

Aims/hypothesis Diabetic peripheral neuropathy (DPN) is one of the major complications of
diabetes, which contributes greatly to morbidity and mortality. There is currently no effective …

Administration of mesenchymal stem cells (MSCs) improves the recovery from acute kidney
injury (AKI). The mechanism may involve paracrine factors promoting proliferation of …

The predominant mechanism by which adipose mesenchymal stem cells (AMSCs)
participate to tissue repair is through a paracrine activity and their communication with the …