The present study aimed to prepare controlled drug delivery systems based on gelatin-
agarose scaffold and its modification by the addition of glass nanoparticles. Three different …

Local delivery of antibiotic into injured bone is a demand. In this work, different scaffolds of
chitosan (C) with or without bioactive glass (G) were prepared using the freeze-drying …

A new bioactive glass-based scaffold was developed for local delivery of drugs in case of
osteomyelitis. Bioactive glass having a new composition was prepared and converted into …

Composite scaffolds of polyvinyl alcohol (PVA) and/or quaternary bioactive glass (46S6
system) containing 5, 10 and 20 wt% ciprofloxacin were prepared by lyophilisation …

Local drug delivery systems to bone have attracted appreciable attention due to their
efficacy to improve drug delivery, healing and regeneration. In this paper, development and …

The current study focused on the fabrication of a well-designed, biocompatible, physically
stable, non-irritating and highly porous gelatin scaffold loaded with controlled-release …

The controlled release of antibiotics is crucial to improving antimicrobial efficacy, reducing
the risk of bacterial resistance, and ensuring a localized therapeutic effect. In this work, In …

Surgical debridement of the dead bone and subsequent systemic antibiotic therapy is often
ineffective in eliminating Staphylococcus aureus infections in osteomyelitic patients. The …

Osteomyelitis caused by drug-resistant pathogens is one of the most important medical
challenges due to high rates of mortality and morbidity, and limited therapeutical options …

Objective. The present study was designed to investigate the potency of BHA-GEL-GA-GEN
pellet as gentamicin (GEN) delivery system matrix which has been cross-linked with …