Theodor Boveri is considered as the “father” of centrosome biology. Boveri's fundamental
findings have laid the groundwork for decades of research on centrosomes. Here, we briefly …

Centrosome duplication is required for proper cell division, and centriole formation is a key
step in this process. This review discusses recent studies in C. elegans that have identified …

Centrioles, together with the surrounding peri-centriolar material (PCM), constitute the
centrosome, a major microtubule-organizing center of animal cells. Despite being critical in …

Centrosomes are the principal microtubule organizing centers (MTOCs) of animal cells and
comprise a pair of centrioles surrounded by pericentriolar material (PCM). Centriole number …

The centrosome consists of a pair of centrioles and a surrounding matrix of pericentriolar
material that anchors microtubule nucleation sites and consequently determines the number …

Uncovering organizing principles of organelle assembly is a fundamental pursuit in the life
sciences. Caenorhabditis elegans was key in identifying evolutionary conserved …

Centrioles are critical for fundamental cellular processes, including signaling, motility, and
division. The extent to which centrioles are present after cell cycle exit in a developing …

Figure 1: Centrosomes can be successfully tracked within C. elegans applying photo-
conversion to Dendra2:: SAS-4 tagged centrioles.(A) Schematic representation of the UV …

The centrosome serves as a structural context for cytoplasmic organization. Recent studies
on mutants of the nematode worm Caenorhabditis elegans have provided new insight into …

Centrosomes consist of a centriole pair surrounded by pericentriolar material (PCM).
Previous work suggested that centrioles are required to organize PCM to form a structurally …