An increased research focus on the lymphatic system has necessitated the development of
reliable in vivo assessments of lymphatic function in rodent models. Here, we provide three …

Background: Whereas functional lymph imaging in rodents is imperative for drug discovery
of lymph therapeutics, noninvasive imaging of propulsive lymph function in rodents has not …

Collecting lymphatic vessels are critical for the transport of lymph and its cellular contents to
lymph nodes for both immune surveillance and the maintenance of tissue-fluid balance …

Techniques to image lymphatic vessel function in either animal models or in the clinic are
limited. In particular, imaging methods that can provide robust outcome measures for …

Recent years have seen a renewed interest in studies of the lymphatic system. This review
addresses the differences between in vivo and ex vivo methods for visualization and …

The ability to quantify collecting vessel function in a minimally invasive fashion is crucial to
the study of lymphatic physiology and the role of lymphatic pump function in disease …

Despite their important physiological and pathophysiological functions, lymphatic
endothelial cells and lymphatic vessels remain less well studied compared to the blood …

Introduction: Near-infrared (NIR) imaging has emerged as a novel imaging modality for
assessing lymphatic function in vivo. While the technique has provided quantitative data …

Since lymphedema rarely develops in the mouse hindlimb, the underlying mechanisms
remain unclear. We herein investigated the resolution of chronic hindlimb lymphedema in …

Over the last 15 years, discovery of key growth factors and specific molecular markers for
lymphatic vessels has enabled a new era of molecular research on the lymphatic vascular …