The aim of this study was to investigate the use of botulinum toxin type A (BoNT-A) injections
and their efficacy on gross motor function for lower limb spasticity in children with spastic …

Wallen MA, O'Flaherty SJ, Waugh M-CA. Functional outcomes of intramuscular botulinum
toxin type A in the upper limbs of children with cerebral palsy: a phase II trial. Arch Phys Med …

Injected in a muscle, the botulinum toxin causes localized and temporary paralysis by acting
on the neuromuscular synapse. Currently, it is widely prescribed for the treatment of limb …

We evaluated gross motor function following botulinum toxin A (BTX-A) injections in the
lower limbs of children with spastic cerebral palsy in a randomized clinical trial, using a …

Botulinum toxin A (BoNT-A) is considered a safe and effective therapy for children with
cerebral palsy (CP), especially in the hands of experienced injectors and for the majority of …

It has been demonstrated that botulinum toxin type A (BTX‐A) injections reduce spasticity
and improve muscle growth in children with spasticity. It has been postulated that BTX‐A …

Background: Cerebral palsy (CP) is the most common cause of childhood disability globally.
Botulinum toxin A injections are widely used to manage limb spasticity in children with CP …

Botulinum neurotoxin type‐A (BoNT‐A) has been used in association with other
interventions in the management of spasticity in children with cerebral palsy (CP) for almost …

Objective: To assess the efficacy of botulinum toxin A injection for the management of
spastic calf muscles in children with cerebral palsy. Data sources: We reviewed all relevant …

Despite several trials showing reductions in tone and improvements in gait, the relation
between botulinum toxin A (BTX-A) dose and response has rarely been investigated. A …