Long-term effect of botulinum toxin (A) in the management of calf spasticity in children with diplegic cerebral palsy.

ZM Hawamdeh, AI Ibrahim, AA Al-Qudah - Europa medicophysica, 2007 - europepmc.org
Aim The aim of this study was to determine possible long-term effects of multi-injections of
botulinum toxin A (BT-A) on muscle tone and functional abilities in children with cerebral …

Long‐term effects of botulinum toxin A in children with cerebral palsy

K Tedroff, F Granath, H Forssberg… - … Medicine & Child …, 2009 - Wiley Online Library
The long‐term effects of botulinum toxin A (BoNT‐A) treatment in children with cerebral
palsy (CP) are still elusive. We studied a prospective clinical cohort of 94 children with …

Managing spasticity in pediatric cerebral palsy using a very low dose of botulinum toxin type A: preliminary report

A Suputtitada - American journal of physical medicine & …, 2000 - journals.lww.com
Objective: To determine if very low doses of botulinum toxin type A (BTX-A) could reduce
spasticity and improve gait in cerebral palsied children when combined with rehabilitation …

Factors predicting the efficacy of botulinum toxin-A treatment of the lower limb in children with cerebral palsy

E Fazzi, I Maraucci, S Torrielli… - Journal of child …, 2005 - journals.sagepub.com
Botulinum toxin A is widely used for spasticity management in children with cerebral palsy,
although outcomes are unpredictable. The aim of this study was to identify criteria for …

Effects of botulinum toxin A on upper limb spasticity in children with cerebral palsy

A Friedman, M Diamond, MV Johnston… - American journal of …, 2000 - journals.lww.com
Objective: Botulinum toxin A inhibits presynaptic release of acetylcholine at the
neuromuscular junction and has reportedly been successful in the treatment of spastic …

Spasticity associated with cerebral palsy in children: guidelines for the use of botulinum A toxin

LA Koman, BP Smith, R Balkrishnan - Pediatric Drugs, 2003 - Springer
Botulinum A toxin produces selective and reversible chemodenervation that can be
employed to balance muscle forces across joints in children with cerebral palsy (CP) …

Effects of botulinum toxin type A on upper limb function in children with cerebral palsy: a systematic review

A Reeuwijk, PEM van Schie, JG Becher… - Clinical …, 2006 - journals.sagepub.com
Objective: To evaluate whether botulinum toxin type A injections improve upper limb function
in children with cerebral palsy. Methods: An extensive search was carried out in PUBMED …

Botulinum toxin in the management of childhood muscle spasticity: comparison of clinical practice of 17 treatment centres

AMO Bakheit - European journal of neurology, 2003 - Wiley Online Library
At least two randomized controlled trials (RCTs) have shown botulinum toxin type A (BtxA) to
be efficacious and safe when used in the management of muscle spasticity in children …

Botulinum toxin-A in children with congenital spastic hemiplegia does not improve upper extremity motor-related function over rehabilitation alone: a randomized …

EAA Rameckers, L Speth, J Duysens… - … and neural repair, 2009 - journals.sagepub.com
Background. Rehabilitation of the upper extremity in children with hemiplegic cerebral palsy
has not been compared to the same intensity of therapy combined with injected botulinum …

Adductor spasticity in children with cerebral palsy and treatment with botulinum toxin type A: the parents' view of functional outcome

F Heinen, M Linder, V Mall, J Kirschner… - European Journal of …, 1999 - Wiley Online Library
Botulinum toxin type A (BTX‐A) has been used successfully to manage spasticity in children
with cerebral palsy. Little has been done to evaluate treatment outcome and satisfaction …