HIF-la induces GLUT-1 expression, and their presence has been evaluated in colorectal
cancer. However, the expressions of GLUT-1 and HIF-lα have not been investigated …

Expression of the transcription factor hypoxia-inducible factor 1 (HIF-1), which plays a key
role in cellular adaptation to hypoxia, was investigated in normal colorectal mucosa (ten) …

Aims and methods: Hypoxia‐inducible factor (HIF‐1) which contains oxygen regulated HIF‐
1α subunit maintains cytoprotective defence against hypoxic injury by induction of numerous …

Hypoxia-inducible factor-1 (HIF-1) is a transcription factor that regulates gene expression in
critical pathways involved in tumor growth and metastases. In our study we evaluated the …

Hypoxia inducible factor 1 alpha subunit (HIF-1α) is induced in hypoxic conditions and plays
a crucial role in the neoangiogenesis and metastasis of cancer. In this study, we aimed to …

BACKGROUND: Hypoxia inducible factor-1 alpha (HIF-1 alpha) has been correlated with
unfavorable prognosis in several cancers. The aim of this study was to investigate the impact …

Background Human four-and-a-half LIM domains 1 (Fhl1) gene has been reported to
achieve cancer suppressive effects. The purpose of this study is to clarify clinical …

Abstract Hypoxia‐inducible factor (HIF)‐1 and HIF‐2 are heterodimeric transcription factors
that mediate the cellular response to hypoxia. Their key regulatory subunits, HIF‐1α and HIF …

The role of hypoxia-inducible factors-1 alpha (HIF-1α) expression in gastric cancer remains
controversial. We performed a systematic review of the literature with meta-analysis …

Regional hypoxia caused by accelerated cell proliferation and overgrowth is an important
characteristic of neoplasm. Hypoxia can cause a series of changes in gene transcription and …