Cryptococcus neoformans is an opportunistic fungal pathogen and the causative agent of
the disease cryptococcosis. Cryptococcosis is initiated as a pulmonary infection and in …

Glucosylceramides (GlcCer) are involved in the regulation of Cryptococcus neoformans
virulence. In the present study, we demonstrate that passive immunization with a …

Cryptococcus neoformans is an encapsulated fungal pathogen that causes
meningoencephalitis. There are no prophylactic tools for cryptococcosis. Previously, our …

Galactoxylomannan (GalXM) is a complex polysaccharide produced by the human
pathogenic fungus Cryptococcus neoformans that mediates profound immunological …

Cryptococcus neoformans is a fungus classified by the World Health Organization as a
critically important pathogen, which poses a significant threat to immunocompromised …

Meningitis due to Cryptococcus neoformans is responsible for upwards of 180,000 deaths
worldwide annually, mostly in immunocompromised individuals. Currently there are no …

ABSTRACT A vaccine capable of protecting at-risk persons against infections due to
Cryptococcus neoformans and Cryptococcus gattii could reduce the substantial global …

Cryptococcosis caused by Cryptococcus neoformans and Cryptococcus gattii affects a large
population and is a cause of significant morbidity and mortality. Despite its public health …

Vaccines are one of the greatest medical accomplishments to date, yet no fungal vaccines
are currently available in humans mainly because opportunistic mycoses generally occur …

Cryptococcus neoformans is a fungal pathogen causing life-threatening
meningoencephalitis in susceptible individuals. Fungal vaccine development has been …