Abstract Purpose of Review Treat-to-target (goal-directed therapy) has been proposed as a
strategy to assist clinicians in selecting the most appropriate initial treatment for osteoporosis …

ABSTRACT The American Society for Bone and Mineral Research and the United States
National Osteoporosis Foundation (NOF) formed a working group to develop principles of …

Objectives: Current clinical practice guidelines identify patients at high risk for fracture who
are likely to benefit from pharmacological therapy and suggest ways to monitor for …

Drug treatment for osteoporosis typically begins with an oral bisphosphonate, regardless of
initial bone mineral density (BMD) or fracture risk, and decisions to continue or change …

Abstract Treat-to-target (TTT) for osteoporosis is a concept for individualizing patient
treatment decisions that focuses on achieving an acceptable level of fracture risk rather than …

The management of osteoporosis is changing—for the better. Perhaps the most progressive
recent step has been the assessment of fracture risk using clinical risk factors through tools …

Patients often start treatment to reduce fracture risk because of a bone mineral density T-
score consistent with osteoporosis (≤− 2.5). Others with a T-score above− 2.5 may be …

The overarching goal of osteoporosis management is to prevent fractures. A goal-directed
approach to long-term management of fracture risk helps ensure that the most appropriate …

A panel of European experts was convened to establish consensus on a treat-to-target
strategy in osteoporosis. Panellists agreed that the ultimate goals of treating osteoporosis …

Background: Osteoporosis is a prevalent disease with substantial individual and
socioeconomic consequences. The challenges faced by physicians include identifying …