Guideline Summary Chronic limb-threatening ischemia (CLTI) is associated with mortality,
amputation, and impaired quality of life. These Global Vascular Guidelines (GVG) are …

Background Patients with chronic limb-threatening ischemia (CLTI) require revascularization
to improve limb perfusion and thereby limit the risk of amputation. It is uncertain whether an …

Critical limb ischemia (CLI) is a clinical syndrome of ischemic pain at rest or tissue loss, such
as nonhealing ulcers or gangrene, related to peripheral artery disease. CLI has a high short …

Key Clinical Points Chronic Limb-Threatening Ischemia Chronic limb-threatening ischemia
typically manifests as ischemic pain in the distal leg or foot while the patient is at rest, as …

OBJECTIVE: To develop a set of suggested objective performance goals (OPG) for
evaluating new catheter-based treatments in critical limb ischemia (CLI), based on evidence …

Recommendations stated in the TASC II guidelines for the treatment of peripheral arterial
disease (PAD) regard a heterogeneous group of patients ranging from claudicants to critical …

The term critical limb ischemia refers to a condition characterized by chronic ischemic at-rest
pain, ulcers, or gangrene in one or both legs attributable to objectively proven arterial …

Lower extremity critical limb ischemia (CLI) represents symptoms related to end-stage
atherosclerotic peripheral arterial disease manifested by rest pain and tissue loss. It is …

Critical limb ischemia (CLI) is the most severe form of peripheral arterial disease and is
associated with a risk of limb loss. This vascular condition is currently treated with limb …

Importance Chronic critical limb ischemia, marked by intractable lower extremity ischemic
rest pain and tissue loss, is a highly morbid condition that leads to the loss of ambulation …