Introduction Defective lymphatic drainage and translocation of B-cells in inflamed (Bin) joint-
draining lymph node sinuses are pathogenic phenomena in patients with severe rheumatoid …

Introduction Rheumatoid arthritis (RA) is a chronic autoimmune disease with episodic flares
in affected joints. However, how arthritic flare occurs only in select joints during a systemic …

Objective To assess differences between lymphatic function in the affected hands of
rheumatoid arthritis (RA) patients with active synovitis and that of healthy controls, using …

Objective To investigate the distribution and alteration of lymphatic vessels and draining
function in knee joints of normal and osteoarthritic mice. Methods For the mouse models of …

We investigated the presence and alteration of lymphatic vessels in joints of arthritic mice
using a whole-slide imaging system. Joints and long bone sections were cut from paraffin …

Introduction Structural reorganisation of the synovium with expansion of fibroblast-like
synoviocytes (FLS) and influx of immune cells is a hallmark of rheumatoid arthritis (RA) …

Background Lymphatic dysfunction exists in tumor necrosis factor transgenic (TNF-Tg) mice
and rheumatoid arthritis (RA) patients. While joint-draining TNF-Tg popliteal lymphatic …

Early diagnosis and effective monitoring of rheumatoid arthritis (RA) are important for a
positive outcome. Instant treatment often results in faster reduction of inflammation and, as a …

Abstract Purpose of Review Rheumatoid arthritis is one of the most common rheumatic and
autoimmune diseases. While it can affect many different organ systems, RA primarily …

Rheumatoid Arthritis (RA) is a chronic systemic autoimmune disease. RA mainly affects the
joints, with inflammation of the synovial membrane, characterized by hyperplasia, neo …