Rheumatoid arthritis (RA) is a prototypical autoimmune disease that causes destructive
tissue inflammation in joints and elsewhere. Clinical challenges in RA include the empirical …

Background Evidence suggests lymphatic function mediates local rheumatoid arthritis (RA)
flares. Yet biologics that target the immune system are dosed systemically via the …

Background Inflammatory arthritis encompasses a group of immune-mediated diseases
characterized by chronic joint inflammation. Despite having pathogenic mechanisms in …

Background: Lymphatic muscle cell (LMC) contractility and coverage of collecting lymphatic
vessels (CLVs) is integral to effective lymphatic drainage and tissue homeostasis. In fact …

Osteoarthritis (OA) is one of the most prevalent musculoskeletal diseases, affecting patients
suffering from pain and physical limitations. Recent evidence indicates a potential …

Rheumatoid arthritis (RA) is a chronic inflammatory disease, associated with inflammation of
the synovial tissue lining joints and tendons, which leads to degradation of underlying …

Inflammatory arthritis is a chronic systemic autoimmune disease of unknown etiology, which
affects the joints. If untreated, these diseases can have a detrimental effect on the patient's …

We know that inflammation is the primary pathogenic event in rheumatoid arthritis (RA)
leading to joint damage and pain, if not treated. Hence, to optimise medical treatment in …

Lymphatic vessels are critical for clearing fluid and inflammatory cells from inflamed tissues
and also have roles in immune tolerance. Given the functional association of the lymphatics …

Introduction Lymphedema is a chronic disorder that occurs commonly after lymph node
removal for cancer treatment and is characterized by swelling, fibrosis, inflammation, and …