Objective Recent studies have uncovered diverse cell types/states in the RA synovium;
however limited data exist correlating these findings with patient-level clinical information …

Handling editor Josef S Smolen Contributors All authors were involved in drafting the letter
or revising it critically for important intellectual content and approved the final manuscript to …

The lymphatic circulatory system has diverse functions in lipid absorption, fluid homeostasis,
and immune surveillance and responds dynamically when presented with infection …

The role of the lymphatic system in maintaining tissue homeostasis and a number of different
pathophysiological conditions has been well established. The complex and delicate …

Objectives We investigated the reciprocal relationship linking fibroblast-like synoviocytes
(FLS) and T lymphocytes in the inflamed RA synovium and subsequently targeted cellular …

Objectives To unravel the hierarchy of cellular/molecular pathways in the disease tissue of
early, treatment-naïve rheumatoid arthritis (RA) patients and determine their relationship …

Objective Recent studies have demonstrated that there is an inverse relationship between
lymphatic egress and inflammatory arthritis in affected joints. As a model, tumor necrosis …

Background The mechanisms by which only some rheumatoid arthritis (RA) patients
respond favorably to TNF blockade are still poorly characterized. The goal of this study was …

The lesion of rheumatoid arthritis (RA) is a tissue infiltrate of inflammatory cells accumulating
in the synovial membrane. Tissue-infiltrating cells are lymphocytes and macrophages; …

Objective: To investigate the clinical significance of lymphoid neogenesis (LN) in rheumatoid
arthritis (RA), the clinicopathological correlates of this process and its evolution after anti …