Genetically encoded, noise-tolerant, auxin biosensors in yeast facilitate metabolic engineering and directed evolution

P Chaisupa, MM Rahman, SB Hildreth, S Moseley… - bioRxiv, 2023 - biorxiv.org
Auxins are important plant growth regulating compounds that are applied in vast quantities
to crops across the globe to control weeds and improve crop quality and yield. Auxins are …

Dynamic context-dependent regulation of auxin feedback signaling in synthetic gene circuits

M Avdovic, M Garcia-Navarrete… - Proceedings of the …, 2023 - National Acad Sciences
Phytohormone auxin plays a key role in regulating plant organogenesis. However,
understanding the complex feedback signaling network that involves at least 29 proteins in …

Design of a biosensor for direct visualisation of auxin

O Herud-Sikimic, AC Stiel, M Ortega-Perez… - bioRxiv, 2020 - biorxiv.org
In plants, one of the most important regulative small molecules is indole-3-acetic acid (IAA)
known as auxin. Its dynamic redistribution plays an essential role in virtually every aspect of …

Toward synthetic plant development

JAN Brophy - Plant Physiology, 2022 - academic.oup.com
The ability to engineer plant form will enable the production of novel agricultural products
designed to tolerate extreme stresses, boost yield, reduce waste, and improve …

The emerging role of auxins as bacterial signal molecules: Potential biotechnological applications

T Krell, JA Gavira, A Roca… - Microbial Biotechnology, 2023 - Wiley Online Library
Microorganisms are exposed in their natural niches to a wide diversity of signal molecules.
Specific detection of these signals results in alterations in microbial metabolism and …

Recapitulation of the forward nuclear auxin response pathway in yeast

E Pierre-Jerome, SS Jang, KA Havens… - Proceedings of the …, 2014 - National Acad Sciences
Auxin influences nearly every aspect of plant biology through a simple signaling pathway;
however, it remains unclear how much of the diversity in auxin effects is explained by …

A synthetic approach reveals extensive tunability of auxin signaling

KA Havens, JM Guseman, SS Jang… - Plant …, 2012 - academic.oup.com
Explaining how the small molecule auxin triggers diverse yet specific responses is a long-
standing challenge in plant biology. An essential step in auxin response is the degradation …

Single-cell-based system to monitor carrier driven cellular auxin homeostasis

E Barbez, M Laňková, M Pařezová, A Maizel… - BMC plant biology, 2013 - Springer
Background Abundance and distribution of the plant hormone auxin play important roles in
plant development. Besides other metabolic processes, various auxin carriers control the …

Harnessing synthetic chemistry to probe and hijack auxin signaling

KU Torii, S Hagihara, N Uchida, K Takahashi - new phytologist, 2018 - Wiley Online Library
Contents Summary 417 I. Introduction 417 II. Auxin analogs 1: Plant growth regulators 418
III. Auxin analogs 2: Molecular genetics and chemical biology 418 IV. Auxin analogs 3 …

On the trail of auxin: Reporters and sensors

V Jedličková, S Ebrahimi Naghani, HS Robert - The Plant Cell, 2022 - academic.oup.com
The phytohormone auxin is a master regulator of plant growth and development in response
to many endogenous and environmental signals. The underlying coordination of growth is …