Research into secondary metabolism (SM) production by fungi has resulted in the discovery
of diverse, biologically active compounds with significant medicinal applications. The fungi …

Ecological diversity in fungi is largely defined by metabolic traits, including the ability to
produce secondary or “specialized” metabolites (SMs) that mediate interactions with other …

Anaerobic fungi (class Neocallimastigomycetes) thrive as low-abundance members of the
herbivore digestive tract. The genomes of anaerobic gut fungi are poorly characterized and …

One of the exciting movements in microbial sciences has been a refocusing and
revitalization of efforts to mine the fungal secondary metabolome. The magnitude of …

Highlights•Secondary metabolites are small, bioactive molecules that function in fungal
ecology.•Genomic sequencing has revealed greater diversity of secondary metabolite …

Filamentous fungi possess great potential as sources of medicinal bioactive compounds,
such as antibiotics, but efficient production is hampered by a limited understanding of how …

Covering: up to 2019 Fungi produce a remarkable diversity of secondary metabolites: small,
bioactive molecules not required for growth but which are essential to their ecological …

Basidiomycota are a large and diverse phylum of fungi. They can make bioactive
metabolites that are used or have inspired the synthesis of antibiotics and agrochemicals …

Lichens are symbiotic associations consisting of a photobiont (algae or cyanobacteria) and
a mycobiont (fungus). They are known to produce a variety of unique secondary metabolites …

Fungi produce a wealth of pharmacologically bioactive secondary metabolites (SMs) from
biosynthetic gene clusters (BGCs). It is common practice for drug discovery efforts to treat …