Integrated manganese (III)-doped nanosystem for optimizing photothermal ablation: Amplifying hyperthermia-induced STING pathway and enhancing antitumor …

J Xia, L Wang, T Shen, P Li, P Zhu, S Xie, Z Chen… - Acta Biomaterialia, 2023 - Elsevier
Despite the great promise initially demonstrated by photothermal ablation (PTA) therapy, its
inability to completely ablate large tumors is problematic, because this has been found to …

[HTML][HTML] NIR responsive nanoenzymes via photothermal ablation and hypoxia reversal to potentiate the STING-dependent innate antitumor immunity

Q Li, M Yang, X Sun, Q Wang, B Yu, A Gong… - Materials Today Bio, 2023 - Elsevier
Despite advances in combined photothermal/immunotherapy of tumor, the therapeutic effect
has been impaired due to hypoxic microenvironment and inadequate immune activation …

Manganese-enriched photonic/catalytic nanomedicine augments synergistic anti-TNBC photothermal/nanocatalytic/immuno-therapy via activating cGAS-STING …

Y Zheng, J Chen, XR Song, MQ Chang, W Feng… - Biomaterials, 2023 - Elsevier
As the clinical efficacy of immunotherapy for triple-negative breast cancer (TNBC) remains
limited, exploring new immunotherapy approaches is still indispensable. Mn 2+ has been …

Multifunctional light-activatable nanocomplex conducting temperate-heat photothermal therapy to avert excessive inflammation and trigger augmented …

L Li, X Liang, T He, X Li, X Huang, N Wang, M Shen… - Biomaterials, 2022 - Elsevier
Photothermal therapy (PTT) has been known as an effective weapon against cancer.
However, the necrosis induced by hyperthermia post PTT can trigger excessive …

Photothermal-triggered immunogenic nanotherapeutics for optimizing osteosarcoma therapy by synergizing innate and adaptive immunity

K Liu, Y Liao, Z Zhou, L Zhang, Y Jiang, H Lu, T Xu… - Biomaterials, 2022 - Elsevier
Inadequate immune response remains a critical cause of immunotherapy failure in various
tumor treatments. Herein, we offer a new approach to achieve a cross-talk between innate …

[HTML][HTML] Ultrasound and laser-promoted dual-gas nano-generator for combined photothermal and immune tumor therapy

XY Li, Y Gao, XZ Liu, XQ Hu, YM Li, JX Sun… - … in Bioengineering and …, 2022 - frontiersin.org
The combination of photothermal therapy (PTT) and immune tumor therapy has emerged as
a promising avenue for cancer treatment. However, the insufficient immune response …

A biomimetic nanoplatform for precise reprogramming of tumor-associated macrophages and NIR-II mediated antitumor immune activation

Y Du, X Qian, F Lin, B Gao, W Wang, H Yang, W Wang… - Acta Biomaterialia, 2023 - Elsevier
The therapeutic effects of photothermal therapy (PTT) are dependent on the photothermal
conversion efficiency of photothermal agents (PTAs) in tumors and the subsequent …

An extendable star-like nanoplatform for functional and anatomical imaging-guided photothermal oncotherapy

X Han, Y Xu, Y Li, X Zhao, Y Zhang, H Min, Y Qi… - ACS …, 2019 - ACS Publications
Combining informative imaging methodologies with effective treatments to destroy tumors is
of great importance for oncotherapy. Versatile nanotheranostic agents that inherently …

Engineered cell-assisted photoactive nanoparticle delivery for image-guided synergistic photodynamic/photothermal therapy of cancer

P Wang, W Wu, R Gao, H Zhu, J Wang… - … applied materials & …, 2019 - ACS Publications
Photoactivated therapy, including photodynamic therapy (PDT) and photothermal therapy
(PTT), is a spatiotemporally precise, controllable, and noninvasive method for tumor therapy …

Nanomaterial-based tumor photothermal immunotherapy

P Xu, F Liang - International journal of nanomedicine, 2020 - Taylor & Francis
In recent years, photothermal therapy (PTT) particularly nanomaterial-based PTT is a
promising therapeutic modality and technique for cancer tumor ablation. In addition to killing …