Heparin‐induced thrombocytopenia (HIT) is a clinical‐pathological disorder; thus, laboratory
testing for the pathogenic platelet‐activating antiplatelet factor 4 (PF 4)/heparin antibodies is …

Heparin‐induced thrombocytopenia (HIT) is a prothrombotic drug reaction caused by
platelet‐activating anti‐platelet factor 4 (PF4)/heparin antibodies. Pathogenic HIT antibodies …

Laboratory testing for heparin-induced thrombocytopenia (HIT) has important shortcomings.
Immunoassays fail to discriminate platelet-activating from nonpathogenic antibodies …

Heparin-induced thrombocytopenia (HIT) is a ÔclinicopathologicÕ syndrome (ie diagnosis
depends on both clinical and pathologic criteria being present)[1]. The ÔclinicalÕ criteria …

The laboratory diagnosis of heparin‐induced thrombocytopenia (HIT) is based on an
enzyme immunoassay combined with a functional test, and serotonin release assay (SRA) is …

Immune heparin-induced thrombocytopenia (HIT) is a distinct immunohematologic
syndrome in which laboratory detection of the pathogenic HIT antibodies is diagnostically …

Heparin-induced thrombocytopenia (HIT) is a clinicopathologic disorder that predisposes to
thrombosis. Diagnosis rests on a compatible clinical picture and laboratory evidence of …

Heparin‐induced thrombocytopenia (HIT) is caused by platelet‐activating antibodies that
recognize platelet factor 4//heparin (PF4/H) complexes. According to the “iceberg model,” …

Heparin-induced thrombocytopenia (HIT) has a distinct clinical profile and unique
pathogenesis. It is caused by platelet-activating IgG antibodies that recognize …

Heparin-induced thrombocytopenia (HIT) is a life-threatening, prothrombotic, antibody-
mediated disorder. To maximize the likelihood of recovery, early and accurate diagnosis is …