Tumor angiogenesis is required for tumor growth and metastasis. Interleukin‐35 (IL35), a
member of the IL12 family, is a dimer composed of IL12A and EBV‐induced gene 3 (EBI3) …

Increasing evidence indicated that insulin-like growth factor binding protein 7 (IGFBP7) was
regarded as a potential tumor suppressor in various human cancers, but its role in gastric …

There was growing evidence that inflammatory responses played significant roles in
malignancies. However, the impact of pro-inflammatory-to-anti-inflammatory factor ratio in …

Background: Insulin-like growth factors (IGF-1) and insulin-like growth factor binding protein-
3 (IGFBP-3) play important roles in cell growth and differentiation. The aim of this work was …

IFN-γ is an antitumor cytokine that inhibits cell proliferation and induces apoptosis after
engagement with the IFN-γ receptors (IFNGR) expressed on target cells, whereas IFN …

Objective Pancreatic cancer is one of the most malignant diseases worldwide. Interferon
regulatory factor (IRF) 1 and IRF2 function as a tumor suppressor and oncoprotein …

The level of pretherapeutic serum interleukin-8 (sIL-8) has been demonstrated to correlate
with chemoresistance in gastric cancer. However, its clinicopathological significance of sIL-8 …

Abstract Interferon γ (IFN-γ), a multifunctional cytokine, was upregulated in the resected
gastric cancer tissue. However, whether IFN-γ is involved in the regulation of gastric cancer …

Background Eukaryotic initiation factor 3 subunit d (eIF3d) is the largest subunit of eIF3,
which is shown to promote protein synthesis in cancer cells. Increased expression of eIF3d …

Background Overall, gastric cancer prognosis remains poor. Detailed characterization of
molecular markers that govern gastric cancer pathogenesis is warranted to establish …