Background It is becoming clear that various cytokines are associated with the spread of
cancer cells. The purpose of this study was to compare interleukin (IL)-6 levels in patients …

Abstract Knowledge of potential tumor markers may improve chemotherapeutic efficacy.
Interleukin‑6 (IL‑6) expression in local tumor tissues is associated with cancer progression …

Background/Aims: Interferon regulatory factor 1 (IRF-1) has been shown to function as a
transcriptional activator or repressor of a variety of target genes. However, its upstream, non …

Simple Summary Colorectal cancer (CRC) is the second most common cause of cancer-
related death worldwide. While the exact causes and prognosis of CRC are complex …

Previous studies have suggested that insulin-like growth factor binding protein-3 (IGFBP-3)
acts as a tumor suppressor in human esophageal squamous cell carcinoma (ESCC). The …

HIF-la induces GLUT-1 expression, and their presence has been evaluated in colorectal
cancer. However, the expressions of GLUT-1 and HIF-lα have not been investigated …

Background Pancreatic cancer (PC) is a highly lethal disease and an increasing cause of
cancer-associated mortality worldwide. Interferon regulatory factors (IRFs) play vital roles in …

We reported that insulin receptor substrate 4 (IRS‐4) levels increased in tissue from
colorectal cancer (CRC) patients and promoted retinoblastoma‐cyclin‐dependent kinase …

Background With the essential role of interleukin-1 signaling in cancer-related inflammation,
IL-1R1, the main receptor for both IL-1α and IL-1β, demonstrated therapeutic potential in …

Background The aim of this study was to determine the clinicopathological features of gastric
cancers with loss of imprinting (LOI) of LIT1. Insulin-like growth factor 2 (IGF2) and H19 in …