▪ Abstract Gap junctions contain hydrophilic membrane channels that allow direct
communication between neighboring cells through the diffusion of ions, metabolites, and …

Gap junctions contain cell–cell communicating channels that consist of multimeric proteins
called connexins and mediate the exchange of low-molecular-weight metabolites and ions …

Connexins constitute a large family of trans-membrane proteins that allow intercellular
communication and the transfer of ions and small signaling molecules between cells …

Gap junctions are specialized cell–cell junctions that directly link the cytoplasm of
neighboring cells. They mediate the direct transfer of metabolites and ions from one cell to …

Connexin proteins make intercellular channels–gap junctions–which provide a direct
pathway for cell–cell signaling in vertebrates. Studies of mice lacking connexin genes have …

Connexins are tetraspan transmembrane proteins that form gap junctions and facilitate
direct intercellular communication, a critical feature for the development, function, and …

Intercellular communication can occur through gap junction channels, which are comprised
of connexin proteins. Therefore, levels of connexins can directly correlate with gap junctional …

Adjacent cells share ions, second messengers and small metabotes through intercellular
channels which are present in gap junctions. This type of intercellular communication …

The vertebrate gap junctions formed by the connexin family of transmembrane proteins
came to the attention of geneticists in 1993 with the identification of mutations linked to a …

Cells in tissues share ions, second messengers, and small metabolites through clusters of
intercellular channels called gap junctions. This type of intercellular communication permits …