Analysis of intronic and exonic reads in RNA-seq data characterizes transcriptional and post-transcriptional regulation
RNA-seq experiments generate reads derived not only from mature RNA transcripts but also
from pre-mRNA. Here we present a computational approach called exon-intron split analysis …
from pre-mRNA. Here we present a computational approach called exon-intron split analysis …
Advancing RNA-seq analysis
BJ Haas, MC Zody - Nature biotechnology, 2010 - nature.com
Advancing RNA-Seq analysis | Nature Biotechnology Skip to main content Thank you for
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Finding the active genes in deep RNA-seq gene expression studies
T Hart, HK Komori, S LaMere, K Podshivalova… - BMC genomics, 2013 - Springer
Background Early application of second-generation sequencing technologies to transcript
quantitation (RNA-seq) has hinted at a vast mammalian transcriptome, including transcripts …
quantitation (RNA-seq) has hinted at a vast mammalian transcriptome, including transcripts …
Trimming of sequence reads alters RNA-Seq gene expression estimates
Abstract Background High-throughput RNA-Sequencing (RNA-Seq) has become the
preferred technique for studying gene expression differences between biological samples …
preferred technique for studying gene expression differences between biological samples …
The impact of amplification on differential expression analyses by RNA-seq
Currently, quantitative RNA-seq methods are pushed to work with increasingly small starting
amounts of RNA that require amplification. However, it is unclear how much noise or bias …
amounts of RNA that require amplification. However, it is unclear how much noise or bias …
RNA‐seq: Basic bioinformatics analysis
F Ji, RI Sadreyev - Current protocols in molecular biology, 2018 - Wiley Online Library
Quantitative analysis of gene expression is crucial for understanding the molecular
mechanisms underlying genome regulation. RNA‐seq is a powerful platform for …
mechanisms underlying genome regulation. RNA‐seq is a powerful platform for …
A scaling normalization method for differential expression analysis of RNA-seq data
MD Robinson, A Oshlack - Genome biology, 2010 - Springer
The fine detail provided by sequencing-based transcriptome surveys suggests that RNA-seq
is likely to become the platform of choice for interrogating steady state RNA. In order to …
is likely to become the platform of choice for interrogating steady state RNA. In order to …
IVT-seq reveals extreme bias in RNA sequencing
NF Lahens, IH Kavakli, R Zhang, K Hayer, MB Black… - Genome biology, 2014 - Springer
Background RNA-seq is a powerful technique for identifying and quantifying transcription
and splicing events, both known and novel. However, given its recent development and the …
and splicing events, both known and novel. However, given its recent development and the …
From RNA-seq reads to differential expression results
From RNA-seq reads to differential expression results | Genome Biology Skip to main content
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RNA-seq: technical variability and sampling
Background RNA-seq is revolutionizing the way we study transcriptomes. mRNA can be
surveyed without prior knowledge of gene transcripts. Alternative splicing of transcript …
surveyed without prior knowledge of gene transcripts. Alternative splicing of transcript …