A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice
H Plovier, A Everard, C Druart, C Depommier… - Nature medicine, 2017 - nature.com
Obesity and type 2 diabetes are associated with low-grade inflammation and specific
changes in gut microbiota composition,,,,,,. We previously demonstrated that administration …
changes in gut microbiota composition,,,,,,. We previously demonstrated that administration …
Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study
C Depommier, A Everard, C Druart, H Plovier… - Nature medicine, 2019 - nature.com
Metabolic syndrome is characterized by a constellation of comorbidities that predispose
individuals to an increased risk of developing cardiovascular pathologies as well as type 2 …
individuals to an increased risk of developing cardiovascular pathologies as well as type 2 …
Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity
Obesity and type 2 diabetes are characterized by altered gut microbiota, inflammation, and
gut barrier disruption. Microbial composition and the mechanisms of interaction with the host …
gut barrier disruption. Microbial composition and the mechanisms of interaction with the host …
Akkermansia muciniphila secretes a glucagon-like peptide-1-inducing protein that improves glucose homeostasis and ameliorates metabolic disease in mice
The gut microbiota, which includes Akkermansia muciniphila, is known to modulate energy
metabolism, glucose tolerance, immune system maturation and function in humans …
metabolism, glucose tolerance, immune system maturation and function in humans …
Next-Generation Beneficial Microbes: The Case of Akkermansia muciniphila
Metabolic disorders associated with obesity and cardiometabolic disorders are worldwide
epidemic. Among the different environmental factors, the gut microbiota is now considered …
epidemic. Among the different environmental factors, the gut microbiota is now considered …
Akkermansia muciniphila inversely correlates with the onset of inflammation, altered adipose tissue metabolism and metabolic disorders during obesity in mice
M Schneeberger, A Everard, AG Gómez-Valadés… - Scientific reports, 2015 - nature.com
Recent evidence indicates that the gut microbiota plays a key role in the pathophysiology of
obesity. Indeed, diet-induced obesity (DIO) has been associated to substantial changes in …
obesity. Indeed, diet-induced obesity (DIO) has been associated to substantial changes in …
Akkermansia muciniphila: paradigm for next-generation beneficial microorganisms
Ever since Akkermansia muciniphila was discovered and characterized two decades ago,
numerous studies have shown that the lack or decreased abundance of this commensal …
numerous studies have shown that the lack or decreased abundance of this commensal …
Akkermansia muciniphila: is it the Holy Grail for ameliorating metabolic diseases?
J Yan, L Sheng, H Li - Gut Microbes, 2021 - Taylor & Francis
The increasing prevalence of metabolic diseases has become a severe public health
problem. Gut microbiota play important roles in maintaining human health by modulating the …
problem. Gut microbiota play important roles in maintaining human health by modulating the …
Function of Akkermansia muciniphila in Obesity: Interactions With Lipid Metabolism, Immune Response and Gut Systems
Y Xu, N Wang, HY Tan, S Li, C Zhang… - Frontiers in …, 2020 - frontiersin.org
Obesity and its metabolic syndrome, including liver disorders and type 2 diabetes, are a
worldwide epidemic and are intimately linked to diet. The gut microbiota interaction has …
worldwide epidemic and are intimately linked to diet. The gut microbiota interaction has …
Revisiting the role of Akkermansia muciniphila as a therapeutic bacterium
Despite a short history since its first isolation, Akkermansia muciniphila has been extensively
studied in relation to its effects on human metabolism. A recent human intervention study …
studied in relation to its effects on human metabolism. A recent human intervention study …