[HTML][HTML] Exogenous recombinant human insulin-induced severe hypersensitivity reaction precipitating hyperglycemic crisis: A clinical conundrum

KU Lijesh, RD Gupta, M SenthilRaja… - Journal of Family …, 2020 - journals.lww.com
Hypersensitivity reactions against exogenous insulin are a rare clinical entity after the
advent of recombinant human insulin; however, there are still case reports wherein patients …

[HTML][HTML] The complexities of insulin allergy: a case and approach

B Aberumand, S Jeimy - Allergy, Asthma & Clinical Immunology, 2021 - Springer
Background Insulin hypersensitivity is rare, but challenging for individuals with diabetes. The
prevalence of insulin allergy has decreased since the introduction of human recombinant …

[PDF][PDF] Human insulin allergy: four case reports

AT Rodrigues, LFC Ensina, LS Garro… - European annals of …, 2010 - researchgate.net
Insulin allergy was not uncommon in the past, but has lowered with the introduction of
human recombinant insulin. Human recombinant insulin allergy is a rare condition, now …

A case report and systematic literature review: insulin-induced type III hypersensitivity reaction

RR Meredith, P Patel, P Huang, CP Onyenekwu… - Frontiers in …, 2024 - frontiersin.org
Insulin-induced type III hypersensitivity reactions (HSRs) are exceedingly rare and pose
complex diagnostic and management challenges. We describe a case of a 43-year-old …

Systemic and local allergy to human insulin

M Wittrup, J Pildal, AK Rasmussen, BG Skov… - Ugeskrift for …, 2003 - europepmc.org
After introduction of recombinant human insulin, immunological reactions have become rare,
but symptomatic immune reactions to insulin still occur. We present four insulin-treated …

Severe insulin allergy successfully treated with continuous subcutaneous insulin infusion

T Fujikawa, H Imbe, M Date, Y Go, H Kitaoka - Diabetes research and …, 2012 - Elsevier
Severe insulin allergy successfully treated with continuous subcutaneous insulin infusion -
ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & Books Search …

Insulin Reactions: What Do You Do When Your Treatment's the Trigger?

M Edwards, C Liy-Wong, A Byrne, KN Cowan… - Canadian Journal of …, 2023 - Elsevier
Discussion Insulin hypersensitivity is an uncommon but devastating condition in patients
with insulin-dependent diabetes and is associated with significant short-and long-term …

[HTML][HTML] Successful management of type IV hypersensitivity reactions to human insulin analogue with injecting mixtures of biphasic insulin aspart and dexamethasone

WL Wen, KB Tsai, YH Lin, SJ Hwang, PJ Hsiao… - Journal of the Formosan …, 2019 - Elsevier
Although hypersensitivity reaction to insulin was supposed to be less-frequent with current
insulin analogue, case reports with different types of allergic reactions to insulin analogue …

[PDF][PDF] A case of cimetidine-induced immediate hypersensitivity

HJ Cho, HS Yoo, SY Park, EM Yang, MG Yoon… - 2012 - repository.ajou.ac.kr
Insulin allergy is now a rare condition thanks to the introduction of human recombinant
proteins in the 1980s. As a high-molecular-weight protein, insulin induces mainly type I …

Successful treatment with continuous subcutaneous insulin infusion for allergy to human insulin and its analogs

L Zhang, M Zhang, YY Liu, M Hu, X Zhou… - Diabetes Research and …, 2011 - Elsevier
Successful treatment with continuous subcutaneous insulin infusion for allergy to human insulin
and its analogs - ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & …