Introduction CO 2 pneumoperitoneum can influence the biological behavior of
neuroblastoma (NB). Angiogenesis and genetic features are responsible for malignant …

Purpose The proto-oncogene MYCN is considered a transcription factor involved in the
regulation of neuroblastoma (NB) cell biology. Since minimally invasive-surgery represents …

The ablative role of minimally invasive surgery (MIS) in neuroblastoma (NB) is still
controversial due to the possible CO₂ pneumoperitoneum side-effects on tumor …

Purpose: It has been reported that CO 2 gas, used to establish a pneumoperitoneum during
laparoscopy, affects the behavior of tumor cells. The proto-oncogenes c-myc and HMGB-1 …

Background: Minimally invasive techniques are increasingly applied to children with
malignant tumors. We showed previously that CO 2 used for pneumoperitoneum modulates …

Purpose Several oxygen-dependent factors, eg, CAIX (carbonic anhydrase IX) or
phosphoglycerate kinase 1 (PGK1) interacting with the CXCR4/SDF1 axis (chemokine …

Objective: To investigate the effects of carbon dioxide (CO2) pneumoperitoneum on the
abdomino-metastatic tumor growth of ovarian carcinoma cell in nude mice and to primarily …

Solid tumours are predisposed to hypoxic conditions due to cellular proliferation outpacing
the rate of angiogenesis. Hypoxia is associated with enhanced tumour aggression. We …

Background Minimally invasive techniques are increasingly used for biopsy and resection of
neuroblastoma, but the impact on the behavior of spilled tumor cells is unknown. We aimed …

Objective To investigate the effects of different CO2 pneumoperitoneum pressures on gastric
cancer cells' growth and proliferation in nude mouse model of implanted tumor. Methods …