In the late 1960s and early 1970s, Freis et al. demonstrated convincingly that the
administration of antihypertensive drugs was associated with a marked reduction in target …

RECENT trends in medical treatment of essential hypertension are definitely towards the
use of combinations of drugs. This is because, in the absence of a known etiology of the …

1. The results of the Veterans Administration Co-operative Study have been extended by the
subsequent clinical trials, which included patients of both sexes and with less vascular …

Despite many advances in antihypertensive treatment, blood pressure control remains far
from perfect in clinical practice. 1, 2 The latest WHO/ISH guidelines3 recommend initiating …

Current blood pressure treatment guidelines call for a single drug to be tried first in people
with Stage 1 hypertension, ie those with a systolic reading over 140 mmHg and a diastolic …

Marvin Moser, MD Editor in Chief www. lejacq. com ID: 2625 combination therapy, Bakris
and colleagues present compelling arguments for their use. Percentages of responders and …

Almost one billion individuals worldwide are currently estimated to be affected by
hypertension, or high blood pressure, with this figure predicted to rise to over 1.5 billion by …

Hypertension remains a significant health problem, affecting approximately 30% of the US
population. Of these, only 36.8% have BP controlled to recommended levels of< 140/90 …

Not uncommonly, to effectively treat hypertension, mul-tiple drugs must be given. Multidrug
combinations that dominate clinical practice typically include a thiazide-type diuretic …

Evidence supports the concept that therapeutic reduction of intra-arterial pressure (blood
pressure) well into the biologically normal range confers substantial protection against death …