The kisspeptin precursor is the protein transcribed from the Kiss-1 gene and the kisspeptins
are the peptides that are posttranslationally processed from the precursor. The kisspeptins …

The neuropeptides kisspeptin (encoded by Kiss1) and RF amide‐related peptide‐3 (also
known as Gn IH; encoded by Rfrp) are potent stimulators and inhibitors, respectively, of …

Recent data indicates that kisspeptin, encoded by the KISS1 gene, could play a role in
transducing metabolic information into the hypothalamic–pituitary–gonadal (HPG) axis, the …

GnRH neurons are the final central pathway controlling fertility. Kisspeptin potently activates
GnRH release via G protein-coupled receptor 54 (GPR54). GnRH neurons express GPR54 …

Kisspeptins, products of the KiSS-1 gene with ability to bind G protein-coupled receptor 54
(GPR54), have been recently identified as major gatekeepers of reproductive function with …

The Kiss1 gene codes for a family of peptides that act as endogenous ligands for the G
protein-coupled receptor GPR54. Spontaneous mutations or targeted deletions of GPR54 in …

The G protein-coupled receptor GPR54, and its peptide ligand kisspeptin (Kp), are crucial for
the induction and maintenance of mammalian reproductive function. GPR54 is expressed by …

Kisspeptin has recently emerged as a key regulator of the mammalian reproductive axis. It is
known that kisspeptin, acting centrally via the kisspeptin receptor, stimulates secretion of …

Kisspeptins, the products of KiSS-1 gene acting via G protein-coupled receptor 54 (GPR54),
have recently emerged as fundamental gatekeepers of gonadal function by virtue of their …

Kisspeptins are products of the KiSS-1 gene, which bind to a G protein-coupled receptor
known as GPR54. Mutations or targeted disruptions in the GPR54 gene cause …