The important role of kisspeptin neurons in the regulation of GnRH neuron activity is now
well accepted. However, the ways in which kisspeptin neurons located in the arcuate …

Kisspeptin is the peptide product of the KiSS‐1 gene and the endogenous agonist for the
GPR54 receptor. Recent evidence suggests the kisspeptin/GPR54 system is a key regulator …

Kisspeptin and its G protein-coupled receptor KISS1R play key roles in mammalian
reproduction due to their involvement in the onset of puberty and control of the hypothalamic …

Gonadotrophin‐releasing hormone (GnRH) is the primary hypothalamic factor responsible
for the control of gonadotrophin secretion in vertebrates. However, within the last decade …

Ovulation is central to mammalian fertility, yet the precise mechanism through which
oestrogen triggers the gonadotrophin‐releasing hormone (GnRH) surge that generates the …

Neuropeptide kisspeptin has been suggested to be an essential central regulator of
reproduction in response to changes in serum gonadal steroid concentrations. However, in …

Kisspeptins, and their G-protein coupled receptor 54 (GPR54), are key components in the
regulation of gonadotropin-releasing hormone (GnRH) secretion in humans and other …

Kisspeptins are neuropeptides encoded by the Kiss1 gene, which have been implicated in
the neuroendocrine regulation of gonadotropin-releasing hormone (GnRH) secretion. The …

The G protein-coupled receptor 54 (GPR54) and its endogenous ligand, kisspeptin, are
essential for activation and regulation of the hypothalamic-pituitary-gonadal axis. Analysis of …

Kisspeptin and its receptor GPR54 have been described as key hypothalamic components
in the regulation of GnRH secretion. Kisspeptin is also present in several regions of the …