Kisspeptin is a potent activator of GnRH-induced gonadotropin secretion and is a proposed
central regulator of pubertal onset. In mice, there is a neuroanatomical separation of two …

Our understanding of kisspeptin and its actions depends, in part, on a detailed knowledge of
the neuroanatomy of the kisspeptin signaling system in the brain. In this chapter, we will …

Kisspeptins, the products of the KiSS-1 gene acting via G protein-coupled receptor 54
(GPR54), have recently emerged as pivotal signals in the hypothalamic network triggering …

Kisspeptins are a family of small peptides that play a key role in the neuroendocrine
regulation of the reproductive function through neural pathways that have not yet been …

Kisspeptin, encoded by Kiss1, stimulates GnRH neurons to govern reproduction. In rodents,
estrogen-sensitive kisspeptin neurons in the anterior ventral periventricular nucleus and …

Kisspeptin, a neuropeptide encoded by Kiss1 gene, plays pivotal roles in the regulation of
reproductive function. Recently various stressors and stress-induced molecules such as …

In 2003, two independent groups of researchers discovered almost simultaneously that
inactivating mutations of the G protein coupled receptor, GPR54, cause hypogonadotropic …

Kisspeptin, the product derived from KiSS‐1, and its cognate receptor, GPR54, both exert a
role in the neuroendocrine control of reproduction by regulating gonadotrophin‐releasing …

Activation of the gonadotropic axis critically depends on sufficient body energy stores, and
conditions of negative energy balance result in lack of puberty onset and reproductive …

Kisspeptin is involved in the control of human reproduction bridging the gap between the
sex steroid levels and feedback mechanisms that control the gonadotropin releasing …