Tobacco carcinogen research to aid understanding of cancer risk and influence policy

H Singhavi, JS Ahluwalia, I Stepanov… - Laryngoscope …, 2018 - Wiley Online Library
Education regarding the health effects associated with tobacco use has made important
progress worldwide over the last few decades. Still, tobacco remains a significant cause of …

Tobacco-related carcinogenesis in head and neck cancer

AR Jethwa, SS Khariwala - Cancer and Metastasis Reviews, 2017 - Springer
Head and neck cancer (head and neck squamous cell carcinoma (HNSCC)) is a devastating
disease. Patients require intensive treatment that is often disfiguring and debilitating. Those …

Trends in smoking, cancer risk, and cigarette promotion current priorities for reducing tobacco exposure

VL Ernster - Cancer, 1988 - Wiley Online Library
Tobacco use in the US is currently responsible for more than 30% of all cancer deaths,
including cancers of the lung, larynx, oral cavity, pharynx, pancreas, kidney, bladder, and …

Biomarkers of tobacco exposure: summary of an FDA-sponsored public workshop

CM Chang, SH Edwards, A Arab… - … Biomarkers & Prevention, 2017 - AACR
Since 2009, the FDA Center for Tobacco Products (CTP) has had the authority to regulate
the manufacturing, distribution, and marketing of tobacco products in order to reduce the …

Biomarkers of tobacco carcinogenesis in diverse populations: challenges and opportunities

A Etemadi, CC Abnet, SM Dawsey… - … , Biomarkers & Prevention, 2023 - AACR
Biomarkers can provide distinct information about cancer risk factors in populations from
diverse ancestries and with different exposure patterns by measuring the internal dose of …

Tobacco carcinogen metabolites and DNA adducts as biomarkers in head and neck cancer: potential screening tools and prognostic indicators

SS Khariwala, D Hatsukami, SS Hecht - Head & neck, 2012 - Wiley Online Library
Head and neck squamous cell carcinoma (HNSCC) is one of many cancers that are strongly
associated with tobacco use. Whereas HNSCC is often seen in tobacco users, many …

Carcinogenic components of tobacco and tobacco smoke: A 2022 update

Y Li, SS Hecht - Food and Chemical Toxicology, 2022 - Elsevier
Tobacco and tobacco smoke contain a complex mixture of over 9500 chemical compounds,
many of which have been recognized as hazardous to human health by regulatory …

Tobacco and cancer: an American Association for Cancer Research policy statement

K Viswanath, RS Herbst, SR Land, SJ Leischow… - Cancer research, 2010 - AACR
The evidence against tobacco use is clear, incontrovertible, and convincing; so is the need
for urgent and immediate action to stem the global tide of tobacco-related death and …

Smokeless tobacco and head and neck cancer: there is risk even without fire.

JH Lee - South Dakota Medicine, 2009 - search.ebscohost.com
The use of smokeless tobacco (primarily moist chewing tobacco) is currently on the rise in
the USA. Smokeless tobacco contains many carcinogens. Multiple large-scale …

Self‐reported Tobacco use does not correlate with carcinogen exposure in smokers with head and neck cancer

SS Khariwala, SG Carmella, I Stepanov… - The …, 2015 - Wiley Online Library
Objectives/Hypothesis Head and neck squamous cell carcinoma (HNSCC) is strongly
associated with tobacco use. We sought to examine the relationship between self‐reported …