A sex-specific comparative analysis of oxidative stress biomarkers predicting the risk of cardiovascular events and all-cause mortality in the general population: a …

MF Bourgonje, AE Abdulle, LM Kieneker… - Antioxidants, 2023 - mdpi.com
Oxidative stress plays a pivotal role in cardiovascular (CV) disease, but current biomarkers
used to predict CV events are still insufficient. In this study, we comparatively assessed the …

[HTML][HTML] Editorial Commentary on the Special Issue “Antioxidant Therapy for Cardiovascular Diseases”—Cutting-Edge Insights into Oxidative Stress and Antioxidant …

G Kwon, KM Gibson, L Bi - Antioxidants, 2024 - mdpi.com
Recent advances in cardiovascular research have increasingly emphasized oxidative stress
as a central mechanism in the pathogenesis and progression of cardiovascular diseases …

Systemic oxidative stress, aging and the risk of cardiovascular events in the general female population

MF Bourgonje, AR Bourgonje, AE Abdulle… - Frontiers in …, 2021 - frontiersin.org
Introduction: Menopause is associated with increased cardiovascular risk, in which oxidative
stress plays a pivotal role. Systemic oxidative stress is reflected by decreased levels of free …

Systemic oxidative stress associates with new-onset hypertension in the general population

AR Bourgonje, MF Bourgonje, A Post… - Free Radical Biology …, 2022 - Elsevier
Background Oxidative stress is known to be involved in the development of hypertension,
but accurate redox biomarkers predicting the risk of developing hypertension are scarce …

Plasma total cysteine and cardiovascular risk burden: action and interaction

B De Chiara, V Sedda, M Parolini… - The Scientific World …, 2012 - Wiley Online Library
We hypothesized that redox analysis could provide sensitive markers of the oxidative
pathway associated to the presence of an increasing number of cardiovascular risk factors …

Systemic oxidative stress is increased in postmenopausal women and independently associates with homocysteine levels

AR Bourgonje, AE Abdulle, AM Al-Rawas… - International journal of …, 2020 - mdpi.com
Oxidative stress plays a pivotal role in the pathogenesis of cardiovascular diseases (CVD).
Postmenopausal women have an increased risk of developing CVD due to decreased …

Serum free thiols predict cardiovascular events and all-cause mortality in the general population: A prospective cohort study

AE Abdulle, AR Bourgonje, LM Kieneker, AM Koning… - BMC medicine, 2020 - Springer
Background Serum free thiols (R-SH, sulfhydryl groups) reliably reflect systemic oxidative
stress. Since serum free thiols are rapidly oxidized by reactive species, systemic oxidative …

Cardiovascular risk stratification based on oxidative stress for early detection of pathology

N Corbacho-Alonso, M Baldán-Martín… - Antioxidants & Redox …, 2021 - liebertpub.com
Aims: Current cardiovascular (CV) risk prediction algorithms are able to quantify the
individual risk of CV disease. However, CV risk in young adults is underestimated due to the …

[HTML][HTML] Biological markers of oxidative stress: applications to cardiovascular research and practice

E Ho, KK Galougahi, CC Liu, R Bhindi, GA Figtree - Redox biology, 2013 - Elsevier
Oxidative stress is a common mediator in pathogenicity of established cardiovascular risk
factors. Furthermore, it likely mediates effects of emerging, less well-defined variables that …

Non-traditional cardiovascular disease risk factors in end-stage renal disease: oxidate stress and hyperhomocysteinemia

C Kitiyakara, J Gonin, Z Massy… - Current Opinion in …, 2000 - journals.lww.com
Studies in experimental animals have shown that oxidative stress and hyperhomocyst (e)
inemia culminate in abnormal vascular and endothelial regulation, functional nitric oxide …