Although spinal cord injury is a catastrophic affliction with numerous victims and a variety of
physiological manifestations, the associated disarray in physiology has yet to be …

Survival after spinal cord injury (SCI), once measured in terms of weeks or months, is now
measured in years, and most survivors of SCI go on to live full lives. The quality of life …

Study design: Literature review. Objectives: Critical review of the literature published on the
physiological alterations caused by spinal cord injury (SCI) and their effect on the …

Study design: Experimental laboratory investigations in paraplegic rats. Objective: In order to
understand why acute spinal cord injury (SCI) changes the disposition of some, but not all …

DISCUSSION Dr. Tator: Could you comment on ways to get pharmacokinetics data for a
given drug? You mentioned HPLC for plasma and tissue drug levels. What about …

Spinal cord injury often results in devastating physical, psychological, and economic
disabilities. Research efforts are directed toward providing prognostic outcome data and …

The absolute bioavailability of oral theophylline in five tetraplegic, five paraplegic and three
control (intact neuraxes) subjects was studied. All were healthy nonobese males between …

The rate and completeness of absorption of gentamicin from muscle (healthy and paralyzed)
and gentamicin disposition kinetics following a single intravenous infusion were studied in …

Although research on neural tissue repair has made enormous progress in recent years,
spinal cord injury remains a devastating condition for which there is still no cure. In fact …

Serum concentration‐time course profiles, serum protein binding, and disposition
parameters of lorazepam (LRZ), a benzodiazepine with sedative‐hypnotic, anxiolytic, and …