With the gaining prevalence of obesity, related risks during pregnancy are rising.
Inflammation and oxidative stress are considered key mechanisms arising in white adipose …

Background Drug metabolism genes are involved in the in vivo metabolic processing of
drugs. In previous research, we found that a high-fat diet affected the transcript levels of …

Adipose tissue is the most important energy metabolism and secretion organ, and these
functions are conferred during the adipogenesis process. However, the cause and the …

Background: The present study aimed to explore the changes in the hepatic metabolic
profile during the evolution of diabetes mellitus (DM) and verify the key metabolic pathways …

Aims Non-alcoholic fatty liver disease (NAFLD) is a common chronic liver disease and lacks
for safe and effective drug to therapy completely. Ginsenoside-Rg1 is one of the main …

Background Type 2 diabetes mellitus (T2DM) is a heterogeneous, metabolic, and chronic
condition affecting vast numbers of the world's population. The related variables and T2DM …

Type 2 diabetes mellitus (T2DM) is a complex metabolic disease with multiple etiologies,
involving both genetic and environmental factors. With changes associated with modern life …

Non-alcoholic fatty liver disease develops from simple steatosis to non-alcoholic
steatohepatitis (NASH), which then potentially develops into liver cirrhosis. It is a serious …

The prevalence of diabetes mellitus has been increasing for decades worldwide. To develop
safe and potent therapeutics, animal models contribute a lot to the studies of the …

Obesity and its related complications have emerged as global health problems; however,
the pathophysiological mechanism of obesity is still not fully understood. In this study …