Spinal cord injury (SCI) is a disastrous event causing irreversible loss of both sensory and
motor function. After SCI, both ascending dorsal column axons and descending corticospinal …

Central nervous system injuries, such as spinal cord injury (SCI), are a leading cause of
disability in young adults. SCIs generally have severe clinical consequences and often lead …

Repair of the injured spinal cord is a major challenge in medicine. The limited intrinsic
regenerative response mounted by adult central nervous system (CNS) neurons is further …

Spinal cord injury (SCI) disrupts the structural and functional connectivity between the higher
center and the spinal cord, resulting in severe motor, sensory, and autonomic dysfunction …

Despite advances in promoting axonal regeneration after acute spinal cord injury (SCI),
elicitation of bridging axon regeneration after chronic SCI remains a formidable challenge …

Spinal cord injury (SCI) causes disturbances in motor and sensory functions leading to
paralysis, the severity of which depends on the spinal level of the injury. Traumatic lesions of …

Regeneration of injured CNS neurons was once thought to be an unachievable goal. Most
patients with significant damage to the spinal cord suffer from permanently impaired …

In an effort to develop therapies for promoting neurological recovery after spinal cord injury,
much work has been done to identify the cellular and molecular factors that control axonal …

One hundred years ago, Ramón y Cajal, considered by many as the founder of modern
neuroscience, stated that neurons of the adult central nervous system (CNS) are incapable …

Spinal cord injury is one of the most devastating conditions that affects the central nervous
system. It can lead to permanent disability and there are around two million people affected …