Staphylococcal enterotoxins can cause toxic shock syndrome and autoimmune diseases.
Circulating T cells from these diseases have a very wide range of expression in particular T …

Abstract Background Staphylococcal enterotoxins (SEs), SE-like (SEl) toxins, and toxic
shock syndrome toxin-1 (TSST-1), produced by Staphylococcus aureus, belong to the …

Superantigens (Sags) induce large-scale stimulation of T lymphocytes by a mechanism
distinct from conventional antigen presentation, involving direct MHC binding and …

Superantigens are able to stimulate T lymphocyte populations expressing T cell antigen
receptors (TCR) belonging to particular Vβ families. Moreover, the presence of these …

Severe bacterial or viral infections can induce a state of immune hyperactivation that can
culminate in a potentially lethal cytokine storm. The classic example is toxic shock …

Staphylococcus enterotoxins and toxic shock syndrome toxin-1 (TSST-1) are members of the
family of staphylococcal exoproteins (SE) which bind specifically to HLA class II molecules …

Staphylococcus aureus can produce a wide variety of exotoxins, including toxic shock
syndrome toxin 1 (TSST-1), staphylococcal enterotoxins, and staphylococcal enterotoxin-like …

The superantigen toxic shock syndrome toxin-1 (TSST-1) is implicated as the major cause of
staphylococcal toxic shock syndrome. The temporal sequence of early signaling events in …

Staphylococcus aureus secretes various toxins that act as superantigens by stimulating a
large fraction of the host's T cells. Toxin binding to variable domains of T cell receptor β …

Staphylococcal exotoxins, staphylococcal enterotoxins AE (SEA-SEE), and toxic shock
syndrome toxin-1 (TSST-1) are potent activators of the immune system and cause a variety …