MicroRNAs in the hypothalamus

M Taouis - Best Practice & Research Clinical Endocrinology & …, 2016 - Elsevier
The brain is considered a major site for microRNA (miRNA) expression; as evidenced by
several studies reporting microarray data of different brain substructures. The hypothalamus …

MicroRNAs in the hypothalamus

B Meister, S Herzer, A Silahtaroglu - Neuroendocrinology, 2014 - karger.com
MicroRNAs (miRNAs) are short (∼ 22 nucleotides) non-coding ribonucleic acid (RNA)
molecules that negatively regulate the expression of protein-coding genes …

Micromanaging the neuroendocrine system–A review on miR‐7 and the other physiologically relevant miRNAs in the hypothalamic–pituitary axis

J Zacharjasz, M Sztachera, M Smuszkiewicz… - FEBS letters - Wiley Online Library
The hypothalamic–pituitary axis is central to the functioning of the neuroendocrine system
and essential for regulating physiological and behavioral homeostasis and coordinating …

Strategies to use microRNAs as therapeutic targets.

E Gentilin, E Degli Uberti, MC Zatelli - Best practice & research …, 2016 - europepmc.org
MicroRNAs (miRNAs) are non-coding RNAs generated from endogenous hairpin-shaped
transcripts that powerfully regulate gene expression at post-transcriptional level. Each …

MicroRNAs and possible role in pituitary adenoma

MC Zatelli, EC degli Uberti - Seminars in reproductive medicine, 2008 - thieme-connect.com
This review reports the current knowledge of microRNA (miRNA) expression in pituitary
adenomas, focusing on recent microarray data. Moreover, a discussion is provided …

Fine-tuning the brain: MicroRNAs

E Vreugdenhil, E Berezikov - Frontiers in neuroendocrinology, 2010 - Elsevier
The brain is of bewildering complexity and numerous genes and signaling molecules have
been described that affect the architecture and functioning of specific neuronal circuits …

Neuroendocrine microRNAs linked to energy homeostasis: Future therapeutic potential

KWY Mak, AF Mustafa, DD Belsham - Pharmacological Reports, 2022 - Springer
The brain orchestrates whole-body metabolism through an intricate system involving
interneuronal crosstalk and communication. Specifically, a key player in this complex …

[HTML][HTML] Regulatory mechanisms of microRNAs in endocrine disorders and their therapeutic potential

SJ Ledesma-Pacheco, AG Uriostegui-Pena… - Frontiers in …, 2023 - frontiersin.org
MicroRNAs (miRNAs) are small endogenous non-coding RNA molecules capable of
regulating gene expression at the post-transcriptional level either by translational inhibition …

[HTML][HTML] Hypothalamic miRNAs: emerging roles in energy balance control

M Schneeberger, AG Gomez-Valadés… - Frontiers in …, 2015 - frontiersin.org
The hypothalamus is a crucial central nervous system area controlling appetite, body weight
and metabolism. It consists in multiple neuronal types that sense, integrate and generate …

Perturbation of hypothalamic microRNA expression patterns in male rats after metabolic distress: impact of obesity and conditions of negative energy balance

S Sangiao-Alvarellos, L Pena-Bello… - …, 2014 - academic.oup.com
The hypothalamus plays a crucial role in body weight homeostasis through an intricate
network of neuronal circuits that are under the precise regulation of peripheral hormones …