Background In utero exposure to obesity is consistently associated with increased risk of
metabolic disease, obesity and cardiovascular dysfunction in later life despite the …

Maternal obesity has a major impact on pregnancy outcomes. There is growing evidence
that maternal obesity has a negative influence on placental development and function …

Introduction In animal models, maternal obesity (OB) leads to augmented risk of offspring
OB. While placental function is influenced by maternal habitus, the effect of maternal obesity …

It is well-accepted that maternal obesity affects fetal development to elevate the risk of
offspring disease, but how this happens is unclear. Understanding placental alterations …

Maternal obesity is increasingly prevalent and is associated with elevated morbidity and
mortality rates in both mothers and children. At the interface between the mother and the …

Evidence suggests that maternal obesity (MO) can aggravate placental function causing
severe pathologies during the perinatal window. However, molecular changes and …

Objective To identify possible mechanisms linking obesity in pregnancy to increased fetal
adiposity and growth, a unique mouse model of maternal obesity associated with fetal …

Maternal obesity is associated with an increased risk of obesity and metabolic disease in
offspring. Increasing evidence suggests that the placenta plays an active role in fetal …

GWAS identified variants associated with birth weight (BW), childhood obesity (CO) and
childhood BMI (CBMI), and placenta is a critical organ for fetal development and postnatal …

Aim The current study investigated the impact of maternal obesity on placental phenotype in
relation to fetal growth and sex. Methods Female C57BL6/J mice were fed either a diet high …