The central nervous system (CNS) is a very unique system with multiple features that
differentiate it from systemic tissues. One of the most captivating aspects of its distinctive …

Microglia are essential cellular components of a well-functioning central nervous system
(CNS). The development and establishment of the microglial population differs from the …

Microglia form a unique population of brain-resident macrophages. Although microglia have
been involved in multiple disorders of the central nervous system (CNS), the issue of …

Microglia are highly specialized tissue macrophages of the brain with dedicated functions in
neuronal development, homeostasis and recovery from pathology Despite their unique …

Microglia are the brain‐resident macrophages tasked with the defense and maintenance of
the central nervous system (CNS). The hematopoietic origin of microglia has warranted a …

Mononuclear macrophages derived from the bone marrow (myeloid cells) are key cellular
components of the innate immune system in different organs. In this minireview, we are …

Microglia are the immune cells of the central nervous system (CNS). They patrol the brain
environment with their ramifications and they respond quickly in the presence of pathogens …

Microglia and macrophages, one a brain-resident, the other a mostly hematogenous cell
type, represent two related cell types involved in the brain pathology in multiple sclerosis …

While bone marrow-derived Ly6Chi monocytes can infiltrate the central nervous system
(CNS) they are developmentally and functionally distinct from resident microglia. Our …

Neuroinflammation is a common feature in neurodegenerative diseases and strategies to
modulate neuroinflammatory processes are increasingly considered as therapeutic options …